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Merck
CN

16633

阿伏苯宗 CRM

analytical standard

别名:

丁基甲氧基二苯甲酰甲烷, 阿伏苯宗

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关于此项目

经验公式(希尔记法):
C20H22O3
化学文摘社编号:
分子量:
310.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
274-581-6
MDL number:
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InChI key

XNEFYCZVKIDDMS-UHFFFAOYSA-N

InChI

1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3

SMILES string

COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C

grade

analytical standard

assay

≥99.0% (GC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

81-84 °C

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

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General description

阿伏苯宗是一种UVA过滤。用于防晒乳液和化妆品配方。它在约340-350 nm处具有最大吸收,在紫外线照射下吸收降低,导致UVA保护作用丧失。它的光稳定性非常敏感,因为它在极性质子溶剂中稳定,而在非极性溶剂中对光不稳定。

Application

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阿伏苯宗可用作以下分析物定量的分析参考标准品:
  • 使用带有二极管阵列检测器的反相高效液相色谱(RP-HPLC-DAD)的防晒制剂。
  • 使用液相色谱-正电喷雾电离-串联质谱法(LC-ESI-MS/MS)在多反应监测模式(MRM)下分析淡水、盐水样品、大鼠血浆和皮肤层

阿伏苯宗可用于研究衍生自4-丁基-4′-甲氧基二苯甲酰甲烷(BM-DBM)的封闭二酮形式的光物理特性,光敏活性。

hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A sensitive LC?ESI-MS/MS method for the quantification of avobenzone in rat plasma and skin layers: Application to a topical administration study
Kim GM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1003, 41-46 (2015)
Analytical method development for simultaneous estimation of Oxybenzone, Octocrylene, Octinoxate and Avobenzone in sunscreen by high performance liquid chromatography and its validation
Bhuva C, et al.
Pharmacophore, 3(2) (2012)
Determination of seven commonly used organic UV filters in fresh and saline waters by liquid chromatography-tandem mass spectrometry
Bratkovics S and Sapozhnikova Y
Analytical Methods : Advancing Methods and Applications, 3(12), 2943-2950 (2011)
Ibrahim Hanno et al.
Pharmaceutical research, 29(2), 559-573 (2011-09-23)
To prepare polyamide nanocapsules for skin photo-protection, encapsulating α-tocopherol, Parsol®MCX (ethylhexyl methoxycinnamate) and/or Parsol®1789 (butyl methoxydibenzoylmethane). Nanocapsules were obtained by combining spontaneous emulsification and interfacial polycondensation reaction between sebacoyl chloride and diethylenetriamine. Nano-emulsions used as control were obtained by the
Tatiana Armeni et al.
Toxicology, 203(1-3), 165-178 (2004-09-15)
As an extension of our previous investigations on sunscreen ingredients, the present work was aimed at assessing the possible protective effects of a common UVA-absorbing agent, Parsol 1789 (4-tert-butyl-4'-methoxydibenzoylmethane) in contact with human keratinocytes under UVA illumination. Cell viability was

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