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Merck
CN

229148

红紫素

Dye content 90 %

别名:

1,2,4-三羟基蒽醌, 吡啉, 羟基氮杂酸

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关于此项目

经验公式(希尔记法):
C14H8O5
化学文摘社编号:
分子量:
256.21
EC Number:
201-359-8
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Colour Index Number:
58205
Beilstein/REAXYS Number:
1887127
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InChI key

BBNQQADTFFCFGB-UHFFFAOYSA-N

InChI

1S/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19H

SMILES string

Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O

assay

>70-85% (HPLC)

form

powder

composition

Dye content, 90%

impurities

1-3% DMF

mp

253-256 °C (lit.)

solubility

NH4OH: 1 mg/mL, clear to turbid

λmax

515 nm, 521 nm (2nd)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

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General description

紫茜素(1,2,4-三羟基蒽醌)是存在于印度茜草(Rubia cordifolia)根中的关键色素。这种色素可产生具有独特耐热和耐光性能的颜色。

Application

组织学中的核染色液

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dyeing studies with hydroxyanthraquinones extracted from Indian madder. Part 1: Dyeing of nylon with purpurin
Gupta D
Coloration Technology (2001)
Optimization of microwave-assisted extraction for alizarin and purpurin in Rubiaceae plants and its comparison with conventional extraction methods.
Dabiri M
Journal of Separation Science, 28, 387-396 (2005)
Tim Marczylo et al.
Journal of agricultural and food chemistry, 51(11), 3334-3337 (2003-05-15)
Purpurin, an anthraquinone constituent from madder root, has previously been reported as antimutagenic in the Ames Salmonella bacterial mutagenicity assay and as antigenotoxic in Drosophila melanogaster, against a range of environmental carcinogens. Short-term dietary supplementation with purpurin inhibits the formation
C J Gomer et al.
Cancer research, 56(10), 2355-2360 (1996-05-15)
Photodynamic therapy (PDT) is an experimental cancer therapy inducing tumor tissue damage via photosensitizer-mediated oxidative cytotoxicity. A previous report indicates that oxidative stress induced by hydrogen peroxide or menadione activates the heat shock transcription factor in mouse cells but does
Modified porphyrins, chlorins, phthalocyanines, and purpurins: second-generation photosensitizers for photodynamic therapy.
M Kreimer-Birnbaum
Seminars in hematology, 26(2), 157-173 (1989-04-01)

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