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36687

4-氨基吡啶

PESTANAL®, analytical standard

别名:

4-吡啶胺, 4AP, 对氨基吡啶, 氨吡啶

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关于此项目

经验公式（希尔记法）:
C5H6N2
化学文摘社编号:
504-24-5
分子量:
94.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329755452
EC Number:
207-987-9
Beilstein/REAXYS Number:
105782
MDL number:
MFCD00006439
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grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

273 °C (lit.)

mp

155-158 °C (lit.)

application(s)

agriculture
environmental

format

neat

SMILES string

Nc1ccncc1

InChI

1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)

InChI key

NUKYPUAOHBNCPY-UHFFFAOYSA-N

Gene Information

human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)

General description

4-Aminopyridine is a small molecule potassium channel blocker, which stimulates the release of glutamate from nerve terminals and induces seizures. It can also be used as a drug that aims to improve ambulatory impairment, a major symptom of multiple sclerosis disease.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

312.8 °F

flash_point_c

156 °C

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

危险化学品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCG8622
BCCD4391
BCCB6978
BCBZ4641
BCBT9646

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4-Aminopyridine ameliorates experimental autoimmune neuritis in Lewis rats
Moriguchi K, et al.
Journal of Neuroimmunology, 305, 72-74 (2017)
Berberine attenuates convulsing behavior and extracellular glutamate and aspartate changes in 4-aminopyridine treated rats
Sadeghnia RH, et al.
Iranian Journal of Basic Medical Sciences, 20, 588-588 (2017)
R I Westphalen et al.
British journal of anaesthesia, 110(4), 592-599 (2012-12-06)
Presynaptic effects of general anaesthetics are not well characterized. We tested the hypothesis that isoflurane exhibits transmitter-specific effects on neurotransmitter release from neurochemically and functionally distinct isolated mammalian nerve terminals. Nerve terminals from adult male rat brain were prelabelled with
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全球贸易项目编号

货号GTIN
F3639-10MG04061833284773
F3639-50MG04061832534671
36687-1G04061831826678