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经验公式(希尔记法):
C20H14N2O3 · HCl
化学文摘社编号:
分子量:
366.80
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
236-944-7
Beilstein/REAXYS Number:
4631860
MDL number:
产品名称
氯化罗丹明 110, Dye content ≥75 %
InChI key
JNGRENQDBKMCCR-UHFFFAOYSA-N
InChI
1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H
SMILES string
Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1
form
powder or crystals
composition
Dye content, ≥75%
mp
>300 °C (lit.)
λmax
496 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
罗丹明110氯化物已被用于合成罗丹明110十八烷基酯(R110C18)。
General description
罗丹明110氯化物(R110)是一种激光级染料。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Sambashiva Banala et al.
ACS chemical biology, 7(2), 289-293 (2011-10-27)
A caged rhodamine 110 derivative for the specific labeling of SNAP-tag fusion proteins is introduced. The caged rhodamine 110 derivative permits the labeling of cell surface proteins in living cells and of intracellular proteins in fixed cells. The probe requires
Aya Shibata et al.
Bioorganic & medicinal chemistry letters, 18(7), 2246-2249 (2008-03-25)
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modification of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions.
Jaime G Mayoral et al.
Applied biochemistry and biotechnology, 160(1), 1-8 (2009-01-28)
A novel end-point fluorimetric procedure based on the use of rhodamine-110-labeled specific substrate was developed to determine trypsin activities in biological samples. We evaluated the ability of trichloroacetic acid and acetic acid to stop the enzymatic reaction without hindering the
Michelle M Martinez et al.
Analytical and bioanalytical chemistry, 396(3), 1177-1185 (2009-11-26)
Early detection of apoptotic cells via caspase activity is demonstrated with fast response time. Fluorescence correlation spectroscopy (FCS) is used to identify the presence of a cleaved fluorogenic probe based on the fluorescence of rhodamine 110 in Jurkat cells. FCS
Melissa M Yatzeck et al.
Bioorganic & medicinal chemistry letters, 18(22), 5864-5866 (2008-07-04)
A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a 'trimethyl lock' that is triggered by cleavage of an ether bond. In vitro, fluorescence was
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