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Merck
CN

44699

迷迭香酸

purum, ≥95.0% (HPLC)

别名:

(R)-O-(3,4-二羟基肉桂酰)-3-(3,4-二羟苯基)乳酸, 3,4-二羟基肉桂酸 ( R )-1-羧基-2-(3,4-二羟基苯基)乙酯

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关于此项目

经验公式(希尔记法):
C18H16O8
化学文摘社编号:
分子量:
360.31
UNSPSC Code:
12352000
Beilstein/REAXYS Number:
2227587
MDL number:
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grade

purum

assay

≥95.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

171-175 °C

SMILES string

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2

InChI

1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1

InChI key

DOUMFZQKYFQNTF-WUTVXBCWSA-N

Biochem/physiol Actions

Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kideney disease treatment, cardioprotection and cancer chemoprevention.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Bo Liang et al.
BMC complementary medicine and therapies, 20(1), 345-345 (2020-11-15)
Guanxin V (GXV), a traditional Chinese medicine (TCM), has been widely used to treat coronary artery disease (CAD) in clinical practice in China. However, research on the active components and underlying mechanisms of GXV in CAD is still scarce. A
Vivek Swarup et al.
Antimicrobial agents and chemotherapy, 51(9), 3367-3370 (2007-06-20)
Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels
Mélanie Dubois et al.
Journal of medicinal chemistry, 51(8), 2575-2579 (2008-03-21)
Rosmarinic acid was reacted with nitrite ions under acidic conditions to give 6'-nitro- and 6',6''-dinitrorosmarinic acids according to the reaction time. Both compounds were active as HIV-1 integrase inhibitors at the submicromolar level. They also inhibited the viral replication in