44699
迷迭香酸
purum, ≥95.0% (HPLC)
别名:
(R)-O-(3,4-二羟基肉桂酰)-3-(3,4-二羟苯基)乳酸, 3,4-二羟基肉桂酸 ( R )-1-羧基-2-（3,4-二羟基苯基）乙酯
等级
purum
方案
≥95.0% (HPLC)
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
171-175 °C (lit.)
171-175 °C
SMILES字符串
OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
InChI
1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
InChI key
DOUMFZQKYFQNTF-WUTVXBCWSA-N
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生化/生理作用
Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kideney disease treatment, cardioprotection and cancer chemoprevention.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
法规信息
新产品
此项目有
Bo Liang et al.
BMC complementary medicine and therapies, 20(1), 345-345 (2020-11-15)
Guanxin V (GXV), a traditional Chinese medicine (TCM), has been widely used to treat coronary artery disease (CAD) in clinical practice in China. However, research on the active components and underlying mechanisms of GXV in CAD is still scarce. A
Giedrius Miliauskas et al.
Journal of natural products, 68(2), 168-172 (2005-02-26)
A hyphenated LC-DAD-SPE-NMR setup in combination with on-line radical scavenging detection has been applied for the identification of radical scavenging compounds in extracts of Rhaponticumcarthamoides. After NMR measurements, the pure compounds were infused into a mass spectrometer. The technique enabled
Mélanie Dubois et al.
Journal of medicinal chemistry, 51(8), 2575-2579 (2008-03-21)
Rosmarinic acid was reacted with nitrite ions under acidic conditions to give 6'-nitro- and 6',6''-dinitrorosmarinic acids according to the reaction time. Both compounds were active as HIV-1 integrase inhibitors at the submicromolar level. They also inhibited the viral replication in
Vivek Swarup et al.
Antimicrobial agents and chemotherapy, 51(9), 3367-3370 (2007-06-20)
Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels
Eun-Ju Yang et al.
Journal of cellular physiology, 228(5), 975-982 (2012-10-09)
High mobility group box 1 (HMGB1) protein is a crucial cytokine that mediates response to infection, injury, and inflammation. Rosmarinic acid (RA) is an important component of the leaves of Perilla frutescens and has neuroprotective, anti-microbial, anti-oxidant, and anti-cancer effects
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