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Merck
CN

46166

地塞米松 21-乙酸酯

VETRANAL®, analytical standard

别名:

9α-氟-16α-甲基-11β,17α,21-三羟基--1,4-孕甾二烯-3,20-二酮-21-乙酸酯, 9α-氟-16α-甲基氢化泼尼松龙-21-乙酸酯, 泼尼松龙乙酸酯

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关于此项目

经验公式(希尔记法):
C24H31FO6
化学文摘社编号:
分子量:
434.50
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-646-8
Beilstein/REAXYS Number:
2342608
MDL number:
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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key

AKUJBENLRBOFTD-RPRRAYFGSA-N

Gene Information

human ... NR3C1(2908)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Carolina Gómez-Gaete et al.
Journal of controlled release : official journal of the Controlled Release Society, 128(1), 41-49 (2008-04-01)
We have combined the therapeutic potential of nanoparticles systems with the ease of manipulation of microparticles by developing a hybrid vector named Trojan particles. We aim to use this new delivery vehicle for intravitreal administration of dexamethasone. Initialy, dexamethasone acetate
Qing-yu Xiang et al.
Archives of pharmacal research, 30(4), 519-525 (2007-05-11)
The objective of the present study was to develop a novel solid lipid nanoparticle (SLN) for the lung-targeting delivery of dexamethasone acetate (DXM) by intravenous administration. DXM loaded SLN colloidal suspensions were prepared by the high pressure homogenization method. The
Suresh Singarayar et al.
Pacing and clinical electrophysiology : PACE, 28(4), 311-315 (2005-04-14)
The aim of this study was to characterize acute and medium-term pacemaker lead performance with the two most commonly used glucocorticosteroids: dexamethasone sodium phosphate and dexamethasone acetate. Forty sets of atrial and ventricular passive-fixation leads containing either dexamethasone sodium phosphate
Mayara M Doile et al.
AAPS PharmSciTech, 9(1), 314-321 (2008-05-01)
Inclusion complexes between dexamethasone acetate (DMA), a poorly water soluble drug, and beta-cyclodextrin (betaCD) were obtained to improve the solubility and dissolution rate of this drug. Phase-solubility profile indicated that the solubility of DMA was significantly increased in the presence
Zhao-xiong Zhou et al.
Acta pharmacologica Sinica, 30(11), 1577-1584 (2009-11-06)
To investigate the in vitro release profile of drugs encapsulated within perfluorocarbon (PFC) nanoparticles (NPs) and their ability to inhibit the activity of vascular smooth muscle cells (SMCs). Dexamethasone phosphate (DxP) or dexamethasone acetate (DxA) was encapsulated into PFC nanoparticles

全球贸易项目编号

货号GTIN
46166-100MG04061834036289

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