方案
≥98.0% (HPLC)
比活
~3300 U/mg
杂质
≤0.002% heavy metals
灼烧残渣
≤0.1% (as SO4)
缺失
≤0.5% loss on drying
mp
180-181 °C (lit.)
182-186 °C
储存温度
2-8°C
SMILES字符串
CC1=C(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)C(C)(C)CCC1
InChI
1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChI key
SHGAZHPCJJPHSC-YCNIQYBTSA-N
基因信息
human ... RARA(5914), RARB(5915), RARG(5916)
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生化/生理作用
全−反式−视黄酸(ATRA)是视黄酸受体(RAR)和视黄醇类 X 受体(RXR)的配体。所结合的RAR和RXR可作为调节正常细胞和恶性细胞的生长和分化的转录因子。细胞色素P450(CYP)可催化ATRA的4-羟基化。视黄酸可使胚胎干细胞成为神经元。
视黄酸受体(RAR)和类视黄醇X受体(RXR)的配体; 引发胚胎干细胞成为神经元。
其他说明
1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)
Review: Retinoic acid metabolism
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Retinoic acid metabolism.
H F DeLuca
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