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D172405

N,N-二甲基-4-亚硝基苯胺

Name: <I>N</I>,<I>N</I>-二甲基-4-亚硝基苯胺
Brand: SIAL

97%, powder or chunks

别名:

4-亚硝基-N,N-二甲基苯胺

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关于此项目

线性分子式:

ONC₆H₄N(CH₃)₂

化学文摘社编号:

138-89-6

分子量:

150.18

NACRES:

NA.47

PubChem Substance ID:

24893522

UNSPSC Code:

12171500

EC Number:

205-343-1

MDL number:

MFCD00002063

Beilstein/REAXYS Number:

607293

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属性

产品名称

N,N-二甲基-4-亚硝基苯胺, ≥97%

Quality Level

100

assay

≥97%

form

powder or chunks

mp

85-87 °C (lit.)

solubility

ethanol: 5% (green to very dark green)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(cc1)N=O

InChI

1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3

InChI key

CMEWLCATCRTSGF-UHFFFAOYSA-N

说明

Application

N,N-二甲基-4-亚硝基苯胺与咪唑一起用于检测细胞中单线态氧的形成。

Biochem/physiol Actions

N,N-二甲基-4-亚硝基苯胺用于检测单线态氧。单线态氧与咪唑反应，并通过氧化作用漂白 N,N-二甲基-4-亚硝基苯胺。漂白N,N-二甲基-4-亚硝基苯胺会在 438 nm 处观察到吸收减少。

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pictograms

GHS02,GHS06

signalword

Danger

hcodes

H251,H301,H315,H317,H319,H335

pcodes

P235 - P261 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

4.2 - Pyrophoric and self-heating hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia.

S Kapur et al.

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Ketamine and PCP are commonly used as selective NMDA receptor antagonists to model the putative hypoglutamate state of schizophrenia and to test new antipsychotics. Recent findings question the NMDA receptor selectivity of these agents. To examine this further, we measured

Influence of the order of reagent addition on NDMA formation during chloramination.

I Marie Schreiber et al.

Environmental science & technology, 39(10), 3811-3818 (2005-06-15)

The formation of the potent carcinogen, N-nitrosodimethylamine (NDMA), during chlorine disinfection has caused significant concern among drinking water and wastewater recycling utilities practicing intentional or unintentional chloramination. Previous research modeled NDMA formation as arising from a reaction between monochloramine and

Intra- and intercellular variations in the repair efficiency of O6-methylguanine, and their contribution to kinetic complexity.

Vassilis L Souliotis et al.

Mutation research, 568(2), 155-170 (2004-11-16)

Following administration to rats of various doses of N-nitrosodimethylamine (NDMA), O(6)-methylguanine (O(6)-meG) was lost from the DNA of four tissues (liver, white blood cells, lymph nodes, bone marrow) over two, sharply demarcated phases with substantially differing repair rates. Repair during

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全球贸易项目编号

货号	GTIN
D172405-100G	04061832342368
D172405-25G	04061833560525