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D2920000

丙吡胺

Name: 丙吡胺
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

双异丙吡胺

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关于此项目

经验公式（希尔记法）:

C₂₁H₂₉N₃O

化学文摘社编号:

3737-09-5

分子量:

339.47

NACRES:

NA.24

PubChem Substance ID:

329798759

UNSPSC Code:

41116107

MDL number:

MFCD00057366

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属性

grade

pharmaceutical primary standard

API family

disopyramide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

InChI

1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)

InChI key

UVTNFZQICZKOEM-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Disopyramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

IA 类抗心律失常药；钠通道阻断剂

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361fd

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effect of disopyramide on left ventricular pressure gradient in hypertrophic obstructive cardiomyopathy in comparison with propranolol--a case report.

T Tokudome et al.

Angiology, 50(4), 331-335 (1999-05-04)

The effect of intravenous administration of disopyramide (total dose 100 mg, bolus 20 mg every 5 minutes) was compared with that of propranolol (total dose 10 mg, bolus 2 mg every 5 minutes) in a patient with hypertrophic obstructive cardiomyopathy.

[Comparison of the efficacy of moricizine and disopyramide in the treatment of ventricular extrasystoles].

J P Fauchier et al.

Archives des maladies du coeur et des vaisseaux, 84(4), 553-560 (1991-04-01)

Moricizine chlorhydrate (Ethmozine), a relatively unknown antiarrhythmic agent in France, is a derivative of Phenothiazine, related to the Vaughan-Williams Class IB drugs. A randomised, double-blind, crossover trial with Disopyramide 600 mg/day after a placebo period in 10 patients with ventricular

Procainamide and disopyramide.

C Ribeiro et al.

European heart journal, 8 Suppl A, 11-19 (1987-03-01)

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全球贸易项目编号

货号	GTIN
D2920000	04061833562703