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Merck
CN

PHR3611

N-亚硝基甲基苯胺 (NMPA)

certified reference material, pharmaceutical secondary standard

别名:

N-Methyl-N-nitrosoaniline, N-Methyl-N-nitrosobenzenamine, N-Methyl-N-phenylnitrosamine, NMPA

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关于此项目

经验公式(希尔记法):
C7H8N2O
化学文摘社编号:
分子量:
136.15
UNSPSC Code:
41116107
NACRES:
NA.24
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1466607

form

methanol solution

CofA

current certificate can be downloaded

packaging

pkg of 1 mL

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

application(s)

pharmaceutical

storage temp.

-10 to -25°C

SMILES string

N(N=O)(C)c1ccccc1

InChI

1S/C7H8N2O/c1-9(8-10)7-5-3-2-4-6-7/h2-6H,1H3

InChI key

MAXCWSIJKVASQC-UHFFFAOYSA-N

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


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溶剂

说明

  • 1000 ug/mL solution in Methanol

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



分析证书(COA)

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商品

Discover the efficient separation six nitrosamine impurities with high reproducibility and precise detection to ensure accurate analysis for regulatory compliance.

This application note describes the LC-MS-based quantitative analysis of known nitrosamine impurities following procedures 1 and 3 as given in USP general chapter <1469>.

相关内容

Accurately detect and quantify trace nitrosamines (NDMA, NDEA, NEIPA, NDIPA, NDBA, etc.) in pharmaceutical drugs using our complete product portfolio and application guides for LC-MS and GC-MS. Order high-quality reference standards, columns, filters & more.


Analytical lifecycle management for comprehensive and universal nitrosamine analysis in various pharmaceutical formulations by supercritical fluid chromatography
Schmidtsdorff, S et al.
Journal of Pharmaceutical and Biomedical Analysis, 197, 113960-113960 (2021)



全球贸易项目编号

货号GTIN
PHR3611-1ML04065267401386