InChI
1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
SMILES string
Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
InChI key
VACCAVUAMIDAGB-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
sulfamethizole
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
Sulfamethizole is a sulfonamide derivative used as an antimicrobial drug for the prevention and cure of bacterial infections in both humans and animals.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Solubility of sulfamethizole in some propylene glycol+ water mixtures at several temperatures.
Delgado D R, et al.
Fluid Phase Equilibria, 322, 113-119 (2012)
Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance.
Kerrn M B, et al.
The Journal of Antimicrobial Chemotherapy, 50(4), 513-516 (2002)
Images in clinical medicine. Actinomycetoma.
Manuelle Viguier et al.
The New England journal of medicine, 372(3), 264-264 (2015-01-15)
Adrian I Campos et al.
Molecular cell, 74(6), 1291-1303 (2019-05-03)
Alternative to the conventional search for single-target, single-compound treatments, combination therapies can open entirely new opportunities to fight antibiotic resistance. However, combinatorial complexity prohibits experimental testing of drug combinations on a large scale, and methods to rationally design combination therapies
Yong-Gang Zhao et al.
Journal of chromatography. A, 1345, 17-28 (2014-05-02)
A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) procedure combined with ultra-fast liquid chromatography-tandem quadrupole mass spectrometry (UFLC-MS/MS). The excellent core-shell
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