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Merck
CN

Y0000046

β-雌二醇 17-戊酸酯

European Pharmacopoeia (EP) Reference Standard

别名:

1,3,5(10)-雌三烯-3,17β-二醇 17-戊酸酯

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关于此项目

经验公式(希尔记法):
C23H32O3
化学文摘社编号:
分子量:
356.50
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2480357
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grade

pharmaceutical primary standard

API family

estradiol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

InChI

1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3

InChI key

RSEPBGGWRJCQGY-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Estradiol valerate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C Egarter et al.
Acta obstetricia et gynecologica Scandinavica, 75(4), 386-393 (1996-04-01)
Two sequential hormone replacement regimens, containing either estradiol valerate plus medroxyprogesterone acetate (E2V/MPA) or conjugated estrogens plus medrogestone (CE/MED), were compared with respect to effects on climacteric symptoms, lipid metabolism, and hemostasis. In an open, multicenter study, 51 perimenopausal women
Sheridan M Hoy et al.
Drugs, 69(12), 1635-1646 (2009-08-15)
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. Estradiol valerate/dienogest demonstrated contraceptive efficacy in a large (n = 1377), noncomparative, multicentre study in women aged
B von Schoultz
Climacteric : the journal of the International Menopause Society, 6 Suppl 2, 24-32 (2003-12-13)
A combination of 2 mg estradiol valerate with 2 mg dienogest (E2V/DNG) (Climodien, Schering AG, Berlin, Gemany) is the first continuous combined postmenopausal hormone replacement therapy (HRT) preparation to contain a progestogen with substantial antiandrogenic activity. A study of its



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货号GTIN
Y000004604061833801857