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Y0000146

纳多洛尔

Name: 纳多洛尔
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₇NO₄

化学文摘社编号:

42200-33-9

分子量:

309.40

NACRES:

NA.24

PubChem Substance ID:

329830865

UNSPSC Code:

41116107

MDL number:

MFCD00079476

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属性

grade

pharmaceutical primary standard

API family

nadolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12

InChI

1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1

InChI key

VWPOSFSPZNDTMJ-UCWKZMIHSA-N

Gene Information

human ... ADRB1(153), ADRB2(154)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nadolol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Nadolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris.

R C Heel et al.

Drugs, 20(1), 1-23 (1980-07-01)

Nadolol is a nonselective beta-adrenoceptor blocking drug without intrinsic sympathomimetic or membrane stabilising activity. Its inherently long duration of activity makes it suitable for once daily administration in both hypertension and angina pectoris, and in these conditions it has been

Nadolol: a new beta-adrenoceptor antagonist.

W H Frishman

The New England journal of medicine, 305(12), 678-682 (1981-09-17)

Norepinephrine inhibition of mesenchymal stem cell and chondrogenic progenitor cell chondrogenesis and acceleration of chondrogenic hypertrophy.

Zsuzsa Jenei-Lanzl et al.

Arthritis & rheumatology (Hoboken, N.J.), 66(9), 2472-2481 (2014-05-14)

Mesenchymal progenitor cell chondrogenesis is the biologic platform for the generation or regeneration of cartilage, but the external influence of the sympathetic nervous system on this process is not yet known. Sympathetic nerve fibers are present in articular tissue, and

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货号	GTIN
Y0000146	04061833794654