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Y0000475

Carboprost trometamol

Name: Carboprost trometamol
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15- methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Carboprost tromethamine

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关于此项目

经验公式（希尔记法）:

C₂₅H₄₇NO₈

化学文摘社编号:

58551-69-2

分子量:

489.64

UNSPSC Code:

41116107

NACRES:

NA.24

MDL number:

MFCD01694769

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属性

grade

pharmaceutical primary standard

API family

carboprost

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

NC(CO)(CO)CO.O[C@H]1[C@H](C([C@H](C1)O)\C=C/[C@@](O)(CCCCC)C)C\C=C\CCCC(=O)O

InChI

1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5+,14-12-;/t16-,17?,18+,19-,21-;/m0./s1

InChI key

UMMADZJLZAPZAW-QFXCEMDRSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carboprost trometamol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

法规信息

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分析证书(COA)

Lot/Batch Number

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Treatment of cyclophosphamide-induced hemorrhagic cystitis with intravesical carboprost tromethamine.

L A Levine et al.

The Journal of urology, 149(4), 719-723 (1993-04-01)

We review our experience with 18 consecutive patients who received intravesical carboprost tromethamine, an F2-alpha prostaglandin, for severe hemorrhagic cystitis following cyclophosphamide chemotherapy. Of the patients 16 were given cyclophosphamide for conditioning before bone marrow transplantation and 2 received the

Combined bladder and uterine rupture following prostaglandin-induced midtrimester abortion: an unreported event.

Umber Agarwal et al.

Acta obstetricia et gynecologica Scandinavica, 82(10), 974-975 (2003-09-06)

A prospective randomised trial to compare the efficacy and safety of hemabate and syntometrine for the prevention of primary postpartum haemorrhage.

R F Lamont et al.

Prostaglandins & other lipid mediators, 66(3), 203-210 (2001-10-02)

In a prospective, open-label, assessor-blind, randomised parallel group study the efficacy and safety of Hemabate (Pharmacia-Upjohn Pharmaceuticals, Milton Keynes, Buckinghamshire) an analogue of 15-methyl-prostaglandin (PGF2alpha) analogue was compared with Syntometrine (Alliance Pharmaceuticals, Chippenham, Wilts) the standard combination of ergometrine and

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全球贸易项目编号

货号	GTIN
Y0000475	04061833803769