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Y0000846

卡洛芬

Name: 卡洛芬
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

6-氯-α-甲基-9 H -咔唑-2-乙酸

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关于此项目

经验公式（希尔记法）:

C₁₅H₁₂ClNO₂

化学文摘社编号:

53716-49-7

分子量:

273.71

NACRES:

NA.24

PubChem Substance ID:

329831186

UNSPSC Code:

41116107

MDL number:

MFCD00079028

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属性

grade

pharmaceutical primary standard

API family

carprofen

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P330 + P331 + P310

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Use of carprofen for the treatment of pain and inflammation in dogs.

S M Fox et al.

Journal of the American Veterinary Medical Association, 210(10), 1493-1498 (1997-05-15)

Most studies of nonsteroidal anti-inflammatory drugs (NSAID) do not demonstrate appreciable differences in efficacy. As awareness of the adverse effects associated with NSAID use increases, safety is becoming the primary concern among physicians when selecting NSAID for use by their

Use of electroencephalography (EEG) to assess CNS changes produced by pesticides with different modes of action: effects of permethrin, deltamethrin, fipronil, imidacloprid, carbaryl, and triadimefon.

Danielle L Freeborn et al.

Toxicology and applied pharmacology, 282(2), 184-194 (2014-12-09)

The electroencephalogram (EEG) is an apical measure, capable of detecting changes in brain neuronal activity produced by internal or external stimuli. We assessed whether pesticides with different modes of action produced different changes in the EEG of adult male Long-Evans

Pituitary adenylate cyclase-activating polypeptide (PACAP) in the bed nucleus of the stria terminalis (BNST) increases corticosterone in male and female rats.

K R Lezak et al.

Psychoneuroendocrinology, 45, 11-20 (2014-05-23)

Single nucleotide polymorphisms (SNP) in the genes for pituitary adenylate cyclase-activating polypeptide (PACAP) and the PAC1 receptor have been associated with several psychiatric disorders whose etiology has been associated with stressor exposure and/or dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. In

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货号	GTIN
Y0000846	04061835123889