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Merck
CN

Y0001099

伐昔洛韦杂质G

European Pharmacopoeia (EP) Reference Standard

别名:

4-(二甲氨基)吡啶, N,N-二甲基-4-吡啶胺, DMAP

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关于此项目

经验公式(希尔记法):
C7H10N2
化学文摘社编号:
分子量:
122.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
110354
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grade

pharmaceutical primary standard

API family

valacyclovir

manufacturer/tradename

EDQM

mp

108-110 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI key

VHYFNPMBLIVWCW-UHFFFAOYSA-N

General description

4-(二甲基氨基)吡啶(DMAP)是受阻醇酰化和化学转化的极佳催化剂。它本质上是高度亲核的。
本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

Application

酰化反应的高效催化剂

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

可能适用相应的销售限制。


signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

target_organs

Nervous system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

255.2 °F

flash_point_c

124 °C



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
Bryan Hoang et al.
International journal of pharmaceutics, 471(1-2), 224-233 (2014-05-24)
Docetaxel (DTX) remains the only effective drug for prolonging survival and improving quality of life of metastatic castration resistant prostate cancer (mCRPC) patients. Despite some clinical successes with DTX-based therapies, advent of cumulative toxicity and development of drug resistance limit
Masahiro Murakami et al.
Acta biomaterialia, 10(11), 4723-4729 (2014-07-20)
The objective of this study is to design a drug delivery system (DDS) for the in vivo promotion of macrophage recruitment. As the drug, a water-insoluble agonist of sphingosine-1-phosphate type 1 receptor (SEW2871) was selected. SEW2871 (SEW) was water-solubilized by



全球贸易项目编号

货号GTIN
Y000109904061833806104