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Merck
CN

B8806

Sigma-Aldrich

2′,7′-双(2-羧乙基)-5(6)-羧基荧光素乙酰氧基甲酯

1 mg/mL in DMSO

别名:

BCECF-AM 溶液, 螺(异苯并呋喃-1(3H),9′-(9H)氧杂蒽)-2′,7′-二丙酸

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关于此项目

EC 号:
MDL编号:
UNSPSC代码:
12171500
NACRES:
NA.47
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描述

Mixture of six isomeric compounds

质量水平

表单

liquid

浓度

1 mg/mL in DMSO

颜色

colorless to yellow

应用

diagnostic assay manufacturing
hematology
histology

储存温度

−20°C

SMILES字符串

CC(=O)OCOC(=O)CCc1cc2c(Oc3cc(OCOC(C)=O)c(CCC(=O)OCOC(C)=O)cc3C24OC(=O)c5cc(ccc45)C(=O)OCOC(C)=O)cc1OCOC(C)=O

InChI

1S/C42H40O21/c1-22(43)52-17-57-34-15-36-32(13-27(34)7-10-38(48)59-19-54-24(3)45)42(31-9-6-29(12-30(31)41(51)63-42)40(50)61-21-56-26(5)47)33-14-28(8-11-39(49)60-20-55-25(4)46)35(16-37(33)62-36)58-18-53-23(2)44/h6,9,12-16H,7-8,10-11,17-21H2,1-5H3

InChI key

NTECHUXHORNEGZ-UHFFFAOYSA-N

应用

2′,7′-双(2-羧乙基)-5(6)-羧基荧光素乙酰氧基甲酯已被用于估算液泡pH和细胞内pH。

生化/生理作用

细胞内荧光pH指示剂。
通过细胞溶质酯酶水解成BCECF。

外形

溶剂为0.1%BCECF AM酯和99.9%DMSO

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

185.0 °F

闪点(°C)

85 °C


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Salil Chanroj et al.
The Journal of biological chemistry, 286(39), 33931-33941 (2011-07-29)
The complexity of intracellular compartments in eukaryotic cells evolved to provide distinct environments to regulate processes necessary for cell proliferation and survival. A large family of predicted cation/proton exchangers (CHX), represented by 28 genes in Arabidopsis thaliana, are associated with
Chengzhi Hu et al.
Lab on a chip, 17(4), 671-680 (2017-01-18)
Pollen tubes are tip-growing plant cells that deliver the sperm cells to the ovules for double fertilization of the egg cell and the endosperm. Various directional cues can trigger the reorientation of pollen tube growth direction on their passage through
Evaluation of intracellular pH regulation and alkalosis defense mechanisms in preimplantation embryos.
Dagilgan S, et al.
Theriogenology, 83, 1075-1084 (2015)
Viraj P Nirwan et al.
Nanomaterials (Basel, Switzerland), 11(2) (2021-03-07)
Herein, we report the fabrication and characterization of novel polycaprolactone (PCL)-based nanofibers functionalized with bare (ligand-free) titanium nitride (TiN) nanoparticles (NPs) for tissue engineering applications. Nanofibers were prepared by a newly developed protocol based on the electrospinning of PCL solutions
A K Ho et al.
The American journal of physiology, 261(4 Pt 1), C642-C649 (1991-10-01)
In rat pinealocytes, activation of alpha 1-adrenergic receptors leads to increases in intracellular pH (pHi). In this study, the role of pHi on adrenergic regulation of cyclic nucleotide accumulation was investigated using ammonium chloride, which increased pHi, and sodium propionate

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