InChI
1S/C17H11N/c1-3-7-15-12(5-1)9-10-14-11-13-6-2-4-8-16(13)18-17(14)15/h1-11H
SMILES string
c1ccc2nc3c(ccc4ccccc34)cc2c1
InChI key
OAPPEBNXKAKQGS-UHFFFAOYSA-N
grade
certified reference material
agency
BCR®
manufacturer/tradename
JRC
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Analysis Note
For more information please see:
BCR158
BCR158
Legal Information
BCR is a registered trademark of European Commission
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
J Molnar et al.
Anticancer research, 13(1), 263-266 (1993-01-01)
Effect of K- and L- molecular orbital regions on expression of antiplasmid and carcinogenic activity was studied with various benz[c]acridine derivatives, tricyclic compounds (acridine orange, phenothiazines) and dibenzoazepine (imipramine). Antiplasmid compounds showed the out-of-phase of molecular orbital in the L-region.
W Levin et al.
Cancer research, 43(10), 4625-4628 (1983-10-01)
Benz[c]acridine (B[c]ACR) and 12 of its derivatives, including the 5 metabolically possible trans-dihydrodiols, the diastereomeric bay-region diol-epoxides, 2 non-bay-region diol-epoxides, and the K-region arene oxide, were tested for tumor-initiating activity on mouse skin. A single topical application of 0.4 to
Benz[c]acridine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 32, 129-134 (1983-12-01)
T Kurihara et al.
Anticancer research, 14(5A), 1811-1822 (1994-09-01)
Resonance energies, circuit resonance energies and bond currents of benz[c]acridines were calculated by Aihara's IRE theory. Consequently, it was shown that these compounds had very stable aromatic characters with positive resonance energies and that the resonance energies per pi-electron values
H Sakagami et al.
Anticancer research, 15(6B), 2533-2540 (1995-11-01)
A series of phenothiazine, benzo[a]phenothiazine and benz[c]acridine derivatives were compared for their ability to induce nucleosome-sized DNA fragmentation (a biochemical hallmark of apoptosis), using agarose gel electrophoresis and a fluorescence activated cell sorter. Significant DNA fragmentation-inducing activity was detected in
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