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Merck
CN

M1511

2-巯基乙磺酸钠

analytical standard, ≥98.0% (titration)

别名:

2-巯基乙磺酸 钠盐, HS-CoM Na, MESNA, 辅酶 M 钠盐

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关于此项目

线性分子式:
HSCH2CH2SO3Na
化学文摘社编号:
分子量:
164.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
243-285-9
Beilstein/REAXYS Number:
3657828
MDL number:
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grade

analytical standard

Quality Level

assay

≥98.0% (titration)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

[Na+].[O-]S(=O)(=O)CCS

InChI

1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1

InChI key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

General description

2-巯基乙烷磺酸钠(Sodium 2-mercaptoethanesulfonate)是一种硫醇化合物,常用作减轻抗癌药物副作用的辅助药物,如氧氮磷环、环磷酰胺和异环磷酰胺。它可与药物的有毒代谢物(如丙烯醛)反应,形成无毒化合物。

Application

此分析标准品也可用于以下用途:
  • 通过胶束电动色谱 (MEKC)联用UV检测和MESNA毛细管衍生化,定量分析人体样品中的2-巯基乙磺酸钠 (MESNA)
  • 开发荧光增强组氨酸稳定金纳米团簇(His-Au NCs)探针,检测美司钠(Uromitexan)样品中的2-巯基乙磺酸钠
  • 高效液相色谱-串联质谱法生物分析大鼠血浆样品中的2-巯基乙磺酸钠
  • 以金胶体为探针,通过表面增强拉曼散射(SERS)法定量分析两种药物制剂(注射剂)中的2-巯基乙磺酸钠

Other Notes

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jun-ichi Nishigaki et al.
Inorganic chemistry, 51(6), 3690-3697 (2012-03-10)
Divalent and trivalent nickel complexes of 1,4,8,11-tetraazacyclotetradecane, denoted as cyclam hereafter, coordinated by methyl coenzyme M (MeSCoM(-)) and coenzyme M (HSCoM(-)) have been synthesized in the course our model studies of methyl coenzyme M reductase (MCR). The divalent nickel complexes
Twalib Ngoma et al.
British journal of haematology, 158(6), 749-762 (2012-08-01)
Prior to the introduction of the International Network for Cancer Treatment and Research (INCTR) protocol INCTR 03-06, survival of patients with Burkitt lymphoma at four tertiary care centres in equatorial Africa was probably no more than 10-20%. The results reported
Muhammad Faizan Nazar et al.
Journal of colloid and interface science, 363(2), 490-496 (2011-08-27)
A viable cost-effective approach employing mixtures of non-ionic surfactants Triton X-114/Triton X-100 (TX-114/TX-100), and subsequent cloud point extraction (CPE), has been utilized to concentrate and recycle inorganic nanoparticles (NPs) in aqueous media. Gold Au- and palladium Pd-NPs have been pre-synthesized



全球贸易项目编号

货号GTIN
M1511-10G04061833652534
M1511-25G04061834040781
M1511-5G04061834040798