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文件

T0500000

丁卡因 盐酸盐

European Pharmacopoeia (EP) Reference Standard

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别名:
4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯, 丁卡因 盐酸盐
经验公式（希尔记法）:
C15H24N2O2 · HCl
CAS号:
136-47-0
分子量:
300.82
MDL编号:
MFCD00038912
PubChem化学物质编号:
329826608
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

tetracaine

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

InChI key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

眼用局部麻醉药；用于脊髓麻醉

生化/生理作用

阻断 Ca2+ 从肌浆网的电压敏感性释放。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

相关产品

产品编号
说明
价格

1650006

丁卡因 盐酸盐, United States Pharmacopeia (USP) Reference Standard

Y0001002

丁卡因 盐酸盐, European Pharmacopoeia (EP) Reference Standard

1649991

丁卡因, United States Pharmacopeia (USP) Reference Standard

1650017

4-(丁基氨基)苯甲酸, United States Pharmacopeia (USP) Reference Standard

1650028

Tetracaine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1466572

4-硝基苯甲酸, United States Pharmacopeia (USP) Reference Standard

Y0002117

丁卡因, European Pharmacopoeia (EP) Reference Standard

PHR9019

4-氨基苯甲醇, reference material

PHR9024

3-氨基苯甲醇, reference material

PHR2236

丁卡因相关化合物B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2261

Tetracaine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2339

4-硝基苯甲酸, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3140

丁卡因, pharmaceutical secondary standard, certified reference material

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301 - H319 - H336

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Quan Wen et al.
Cornea, 32(2), 179-184 (2012-08-08)
Our recent tissue cross-linking studies have raised the possibility of using aliphatic β-nitroalcohols (BNAs) for pharmacologic, therapeutic corneal cross-linking. The present study was performed to determine the permeability of BNAs and to explore the use of permeability-enhancing agents. Ex vivo
Patrick E McCleskey et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(1 Pt 1), 82-91 (2013-01-03)
Few published studies have analyzed serum lidocaine levels and individual patient characteristics affecting metabolism after application of compounded topical anesthetics. To measure serum lidocaine levels during and cutaneous side effects after standardized application of 23% lidocaine/7% tetracaine compounded anesthetic to
K Ruetzler et al.
British journal of anaesthesia, 109(5), 790-796 (2012-07-27)
Arterial catheterization is painful and is associated with patient stress and anxiety. Analgesia is usually provided by subcutaneous injection of local anaesthetic. An alternative is topical anaesthesia, such as Rapydan which is a novel topical anaesthetic patch containing 70 mg
Gabriel C Gaviola et al.
The Laryngoscope, 123(4), 852-858 (2013-02-14)
Transnasal endoscopy is commonly performed in an outpatient otolaryngology setting. Patients are typically administered a topical anesthetic and decongestant prior to this procedure to alleviate discomfort and improve visualization. There is no consensus on which topical anesthetic is most effective
Karen L Sharrow-Reabe et al.
Journal of the American Veterinary Medical Association, 241(12), 1645-1649 (2012-12-12)
To compare the corneal anesthetic effects and duration of action of 2 ophthalmic anesthetic agents in horses. Prospective, randomized masked crossover study. 8 clinically normal adult horses. Corneal sensitivity was determined by measuring each eye's corneal touch threshold (CTT) with
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