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Merck
CN

T9681

凝血酶 来源于牛血浆

lyophilized powder, ≥700 NIH units/mg protein (Bradford)

别名:

IIa 因子

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化学文摘社编号:
UNSPSC Code:
12352204
EC Number:
232-648-7
MDL number:
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form

lyophilized powder

specific activity

≥700 NIH units/mg protein (Bradford)

UniProt accession no.

storage temp.

−20°C

Gene Information

cow ... F2(280685)

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Biochem/physiol Actions

丝氨酸蛋白酶,选择性断开纤维蛋白原中的精氨酸-甘氨酸键,形成纤维蛋白以及纤维蛋白肽 A 和 B。

Physical form

Lyophilized from Tris buffer and sodium chloride

Analysis Note

基于 Biggs 改性法的 NIH 分析过程使用 0.2mL 稀释血浆(由血浆与等量生理盐水混合制得)作为底物,以及 0.1mL 凝血酶样品(在含 1% 白蛋白缓冲液中保持稳定)。只使用 15-25 秒之间的凝血时间分析凝血酶浓度。
活性是通过与一种K批次的NIH凝血酶参考标准品进行直接比较而得到并以NIH单位进行表达的。

Other Notes

Activity is expressed in NIH units obtained by direct comparison to a NIH thrombin reference standard.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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Hans P Kohler
Blood, 121(11), 1931-1932 (2013-03-16)
In this issue of Blood, Smith and colleagues report on the functional role of the interaction between these 2 proteins by studying the involved binding sites responsible for clot stabilization.(1)
Stephen R Clark et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(15), 5875-5880 (2013-03-27)
Aminophospholipid (APL) trafficking across the plasma membrane is a key event in cell activation, apoptosis, and aging and is required for clearance of dying cells and coagulation. Currently the phospholipid molecular species externalized are unknown. Using a lipidomic method, we
The reply.
Peter R Kowey et al.
The American journal of medicine, 126(4), e23-e23 (2013-03-20)
Dilyara Cheranova et al.
Journal of visualized experiments : JoVE, (72)(72), doi:10-doi:10 (2013-02-22)
The characterization of gene expression in cells via measurement of mRNA levels is a useful tool in determining how the transcriptional machinery of the cell is affected by external signals (e.g. drug treatment), or how cells differ between a healthy
Response.
Sarah T Garber et al.
Journal of neurosurgery, 118(2), 485-485 (2013-03-16)

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