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Merck
CN

Y0000511

Dexamethasone isonicotinate for impurity C identification

European Pharmacopoeia (EP) Reference Standard

别名:

Dexamethasone 21-isonicotinate

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关于此项目

经验公式(希尔记法):
C28H32FNO6
化学文摘社编号:
分子量:
497.56
UNSPSC Code:
41116107
NACRES:
NA.24
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产品名称

Dexamethasone isonicotinate for impurity C identification, European Pharmacopoeia (EP) Reference Standard

SMILES string

F[C@@]21[C@H]([C@H]4[C@@]([C@@]([C@@H](C4)C)(O)C(=O)COC(=O)c5ccncc5)(C[C@@H]2O)C)CCC3=CC(=O)C=C[C@@]31C

InChI

1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

InChI key

BQTXJHAJMDGOFI-NJLPOHDGSA-N

grade

pharmaceutical primary standard

API family

dexamethasone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Application

Dexamethasone isonicotinate for impurity C identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[Notes on the disaster in Bhopal].
W F Diller
Deutsche medizinische Wochenschrift (1946), 110(45), 1749-1751 (1985-11-08)
Thomas Wittek et al.
Berliner und Munchener tierarztliche Wochenschrift, 118(3-4), 140-149 (2005-04-05)
The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows received
Effect of dexamethasone isonicotinate on milk yield in ketotic cows.
H Philipp et al.
The Veterinary record, 128(18), 427-427 (1991-05-04)
N E Robinson et al.
Equine veterinary journal, 34(1), 17-22 (2002-01-31)
This study used a cross-over design to compare the efficacy of 3 corticosteroids for the relief of airway obstruction and inflammation in 9 heaves-affected horses. The severity of airway obstruction and inflammation was quantified by measurement of lung function and
Jorge Elizondo-Rodriguez et al.
Foot & ankle international, 34(1), 8-14 (2013-02-07)
The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis. The patients were randomly divided into 2 groups according to the treatment received.

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