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Merck
CN

Z2251

Zinquin 乙酯

≥95% purity (HPLC), solid

别名:

2-甲基-8-[(4-甲基苯基)磺酰基氨基]-6-(乙氧羰基甲氧基)喹啉

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关于此项目

经验公式(希尔记法):
C21H22N2O5S
分子量:
414.47
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
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产品名称

Zinquin 乙酯, ≥95% (HPLC), solid

SMILES string

CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c3nc(C)ccc3c1

InChI

1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3

InChI key

KCASTCXJTDRDFT-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble, methanol: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

Biochem/physiol Actions

用于紫外荧光检测细胞中的锌。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yu Gong et al.
Journal of applied toxicology : JAT, 37(8), 895-901 (2016-11-20)
Recent studies showed that ZnO nanoparticles (NPs) might induce the toxicity to human endothelial cells. However, little is known about the interaction between ZnO NPs and circulatory components, which is likely to occur when NPs enter the blood. In this
Abrogation of Nuclear Factor-?B Activation Is Involved in Zinc Inhibition of Lipopolysaccharide-Induced Tumor Necrosis Factor-a Production and Liver Injury
Zhanxiang Z
The American Journal of Pathology (2004)
Correlation of apoptosis with change in intracellular labile Zn(ll) using
Zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid],
a new specific fluorescent probe for Zn(ll)
Peter D
The Biochemical Journal (1993)
Xianqiang Li et al.
Toxicology mechanisms and methods, 28(7), 520-528 (2018-04-27)
It is recently shown that biological macromolecules in food could interact with nanoparticles (NPs) and consequently change the biological effects of NPs. In this study, the interactions between ZnO NPs with or without hydrophobic surface coating and bovine serum albumin
Sarah R Aldhaheri et al.
Free radical biology & medicine, 112, 445-451 (2017-08-29)
In light of the recent lead contamination of the water in Flint, Michigan and its potential adverse outcomes, much research and media attention has turned towards the safety profile of commonly used chelators. Dimercapto-1-propanesulfonic acid (DMPS) typically used in the

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