83695
氯化罗丹明 110
suitable for fluorescence, BioReagent, ≥99.0% (UV)
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关于此项目
经验公式（希尔记法）:
C20H14N2O3 · HCl
化学文摘社编号:
分子量:
366.80
Beilstein:
4631860
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥99.0% (UV)
表单
crystals
mp
>300 °C (lit.)
溶解性
ethanol: soluble
methanol: soluble
荧光
λex 498 nm; λem 520 nm in methanol
适用性
suitable for fluorescence
SMILES字符串
Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1
InChI
1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H
InChI key
JNGRENQDBKMCCR-UHFFFAOYSA-N
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一般描述
罗丹明110或R110是一种三苯甲烷染料，可发射出强烈的绿色荧光。能发出高强度荧光是由于存在作为给电子基团的氨基。罗丹明110的最大激发光谱和发射光谱分别为502.4/521.6521.6 nm。
应用
罗丹明110被用于测定具有准确的动力学参数的蛋白酶活性。它被用于测量诱导细胞凋亡的半胱天冬酶活性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Xian Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(8), 1667-1672 (2003-05-09)
A simple and sensitive fluorescence quenching method for the determination of trace nitrite has been developed. The method is based on the reaction of Rhodamine 110 with nitrite in acidic medium to form a new compound, which has much lower
Sambashiva Banala et al.
ACS chemical biology, 7(2), 289-293 (2011-10-27)
A caged rhodamine 110 derivative for the specific labeling of SNAP-tag fusion proteins is introduced. The caged rhodamine 110 derivative permits the labeling of cell surface proteins in living cells and of intracellular proteins in fixed cells. The probe requires
H Hug et al.
Biochemistry, 38(42), 13906-13911 (1999-10-21)
Caspases (cysteine aspartate-specific proteases) are a structurally related group of cysteine proteases that cleave peptide bonds following specific recognition sequences. They play a central role in activating apoptosis of vertebrate cells. To measure apoptosis induced by various stimuli and at
Aya Shibata et al.
Bioorganic & medicinal chemistry letters, 18(7), 2246-2249 (2008-03-25)
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modification of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions.
Saijie Zhu et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37(5), 573-580 (2009-05-16)
The present study was aimed to investigate the effects of polyoxyethylene (40) stearate (PS), a non-ionic surfactant, on the activity of P-glycoprotein (P-gp) and six major cytochrome P450 (CYP) isoforms. An in vitro diffusion chamber system was utilized to estimate
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