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关于此项目
Biological source:
bovine
Assay:
≥98% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
ligand binding assay: suitable
Impurities:
≤8.0% water (Karl Fischer)
biological source
bovine
Quality Level
assay
≥98% (agarose gel electrophoresis)
form
lyophilized powder
packaging
poly bottle of
origin
New Zealand origin
technique(s)
ligand binding assay: suitable
impurities
≤8.0% water (Karl Fischer)
pH
4.8-7.5
solubility
H2O: soluble 50 mg/mL
UniProt accession no.
foreign activity
protease, essentially free
storage temp.
2-8°C
Gene Information
bovine ... ALB(280717)
General description
The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.
Application
Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.
Biochem/physiol Actions
BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。
Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.
Preparation Note
血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。 从此,有些人便开始使用“Fraction V”这一术语来描述血清白蛋白,无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白,而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白,包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。
采用色谱法纯化
Sourced and manufactured in New Zealand
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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| 货号 | GTIN |
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