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D1156

N , N -二甲基甘氨酸

Name: <I>N </I> , <I> N </I>-二甲基甘氨酸
Brand: SIGMA

≥99%, suitable for ligand binding assays

别名:

（二甲氨基）乙酸

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关于此项目

线性分子式:

(CH₃)₂NCH₂COOH

化学文摘社编号:

1118-68-9

分子量:

103.12

NACRES:

NA.26

PubChem Substance ID:

24893366

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

214-267-8

MDL number:

MFCD00004283

Beilstein/REAXYS Number:

1700261

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属性

产品名称

N , N -二甲基甘氨酸, ≥99%

Quality Level

200

assay

≥99%

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

178-182 °C (lit.)

application(s)

peptide synthesis

SMILES string

CN(C)CC(O)=O

InChI

1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)

InChI key

FFDGPVCHZBVARC-UHFFFAOYSA-N

说明

Biochem/physiol Actions

N,N-二甲基甘氨酸 (DMG) 是一种天然 N-甲基化甘氨酸，用于与其他 N-甲基化甘氨酸（如肌氨酸和 β信息。N，N-二甲基甘氨酸用于开发基于甘氨酸的离子液体和乳化剂。N,N-二甲基甘氨酸作为 COPD 患者蛋白质降解的生物标志物可能有用。DMG 被用作识别、区分和表征氨基酸甲基转移酶的底物。

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.

B A Binzak et al.

American journal of human genetics, 68(4), 839-847 (2001-03-07)

Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and

Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis.

Sheila M Innis et al.

The American journal of clinical nutrition, 93(3), 564-568 (2011-01-14)

Choline is an important constituent of acetylcholine. Choline is needed for acetylcholine in the nonneuronal acetylcholine system that includes epithelial cells of the lung and intestine, endothelial cells, and immune cells. Plasma free choline concentrations are low in children with

Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans.

Jian Yan et al.

The American journal of clinical nutrition, 95(5), 1060-1071 (2012-03-16)

In 1998 choline Adequate Intakes of 425 and 450 mg/d were established for nonpregnant and pregnant women, respectively. However, to our knowledge, no dose-response studies have been conducted to evaluate the effects of pregnancy or maternal choline intake on biomarkers

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全球贸易项目编号

货号	GTIN
D1156-10MG	04061833558805
D1156-5G	04061833558812
D1156-10G	04061833558799
D1156-25G	04061832416137