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D6665

2′,7′-二氯荧光素

Name: 2&#8242;,7&#8242;-二氯荧光素
Brand: SIGMA

~90% purity (TLC) (85- 100% purity), powder

别名:

二氯荧光素；荧光素27

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关于此项目

经验公式（希尔记法）:

C₂₀H₁₀Cl₂O₅

化学文摘社编号:

76-54-0

分子量:

401.20

NACRES:

NA.47

PubChem Substance ID:

24894041

UNSPSC Code:

12171500

EC Number:

200-968-6

MDL number:

MFCD00005047

Beilstein/REAXYS Number:

58009

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属性

产品名称

2′,7′-二氯荧光素, suitable for use as an indicator in chloride titration, ~90% (TLC), powder

Quality Level

200

assay

~90% (TLC)

form

powder

technique(s)

titration: suitable

mp

280 °C (dec.) (lit.)

solubility

ethanol: 25 mg/mL

density

0.79 g/cm³

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1cc2Oc3cc(O)c(Cl)cc3C4(OC(=O)c5ccccc45)c2cc1Cl

InChI

1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H

InChI key

VFNKZQNIXUFLBC-UHFFFAOYSA-N

说明

General description

2′,7′-二氢荧光素是一种氧化敏感荧光探针。2′7′-二氯荧光素二乙酸酯在活性氧（活性氧）存在下氧化成2′7′-二氯荧光素。引用

Application

2 & # 8242；，7 & # 8242；-二氯荧光素已被用作氧化敏感荧光探针来测量细胞中活性氧（活性氧）的形成。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Molecular Vision, 17, 3371-3378 (2011)

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Vittoria Buccigrossi et al.

PloS one, 9(6), e99830-e99830 (2014-06-12)

Rotavirus (RV) infection causes watery diarrhea via multiple mechanisms, primarily chloride secretion in intestinal epithelial cell. The chloride secretion largely depends on non-structural protein 4 (NSP4) enterotoxic activity in human enterocytes through mechanisms that have not been defined. Redox imbalance

Homocysteine induces oxidative-nitrative stress in heart of rats: prevention by folic acid.

Janaína Kolling et al.

Cardiovascular toxicology, 11(1), 67-73 (2010-11-16)

Hyperhomocysteinemia is a risk factor for cardiovascular disease, stroke, and thrombosis; however, the mechanisms by which homocysteine triggers these dysfunctions are not fully understood. In the present study, we investigated the effect of chronic hyperhomocysteinemia on some parameters of oxidative

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货号	GTIN
D6665-5G	04061835347520
D6665-25G	04061833587812