G007
去甲槟榔次碱 盐酸盐
≥97% (NMR), solid
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关于此项目
经验公式（希尔记法）:
C6H9NO2 · HCl
化学文摘社编号:
分子量:
163.60
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Quality Level
assay
≥97% (NMR)
form
solid
color
white
solubility
H2O: soluble, ethanol: slightly soluble
SMILES string
Cl.OC(=O)C1=CCCNC1
InChI
1S/C6H9NO2.ClH/c8-6(9)5-2-1-3-7-4-5;/h2,7H,1,3-4H2,(H,8,9);1H
InChI key
FGNUNVVTHHKDAM-UHFFFAOYSA-N
Gene Information
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Biochem/physiol Actions
GABA uptake inhibitor.
Features and Benefits
This compound is featured on the GABA Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Solutions may be stored for several days at 4 °C.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Betel nut constituents as inhibitors of gamma-aminobutyric acid uptake.
G A Johnston et al.
Nature, 258(5536), 627-628 (1975-12-18)
D N Krause et al.
Brain research, 225(2), 319-332 (1981-11-30)
The interaction of GABA (gamma-aminobutyric acid) and structurally-related compounds with postsynaptic GABA receptors was studied quantitatively by measuring receptor-mediated increases in membrane input conductance in isolated crayfish stretch receptor neurons (SRN). The following compounds, in order of decreasing potency, were
C Rovira et al.
Neuroscience, 12(2), 543-555 (1984-06-01)
In rats under urethane anaesthesia gamma-aminobutyric acid agonists and uptake blockers were microiontophoretically applied in the pyramidal layer of CA1 and in the apical dendrites using a twin set of multibarrelled micropipettes. Thus, the somatic and dendritic field potentials elicited
Xinran Xiang et al.
PloS one, 6(1), e14640-e14640 (2011-02-10)
Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates. Tumor microenvironments, however, are difficult to study in vitro. Cells cultured as monolayers exhibit less resistance to therapy than those grown in vivo and an alternative research model more
Ryan B Griggs et al.
Neuroreport, 26(9), 522-527 (2015-05-27)
Gabapentin reduces behavioral signs of stimulus-evoked allodynia and hyperalgesia in preclinical studies of traumatic nerve injury, but its effects on more clinically relevant measures of stimulus-independent pain are unclear. To address this gap, we determined whether gabapentin would relieve affective
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 5049070001 | 04055977263657 |
| G007-250MG | 04061832090900 |
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