I2760
(-)-异丙肾上腺素 (+)-酒石酸氢盐
β-adrenoceptor agonist, powder
别名:
(-)-异丙去甲肾上腺素 (+)-酒石酸氢盐
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关于此项目
经验公式（希尔记法）:
C11H17NO3 · C4H6O6
化学文摘社编号:
分子量:
361.34
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
产品名称
(-)-异丙肾上腺素 (+)-酒石酸氢盐, powder
form
powder
Quality Level
color
white to off-white
solubility
H2O: ≥50 mg/mL, clear, colorless to faintly yellow
originator
Sanofi Aventis
SMILES string
O[C@@H]([C@H](O)C(O)=O)C(O)=O.CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.C4H6O6/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;5-1(3(7)8)2(6)4(9)10/h3-5,7,11-15H,6H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
InChI key
LBOPECYONBDFEM-RWALOXMOSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
Application
(−)-Isoproterenol (+)-bitartrate salt has been used:
- as a component in KRH medium for cyclic adenosine monophosphate (cAMP) assay
- to stimulate preadipocytes to study its concentration responsive curve
- to intraperitoneally administer to mice to evaluate whether the multi-dry-electrode plate (MDEP)-sensor system can assess drug responses
Biochem/physiol Actions
Isoproterenol functions as an ovine pulmonary vein dilator.
β-肾上腺素受体激动剂；增加细胞溶质 cAMP。
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Jennifer N Gelinas et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(13), 3294-3303 (2005-04-01)
Long-term potentiation (LTP) is activity-dependent enhancement of synaptic strength that can critically regulate long-term memory storage. Like memory, LTP exhibits at least two mechanistically distinct temporal phases. Early LTP (E-LTP) does not require protein synthesis, whereas the late phase of
A Hartzshtark et al.
Experientia, 41(3), 378-379 (1985-03-15)
Local, externally applied pharmacological agents which are assumed to raise the c-AMP level, decrease the low pressure indentation value of the forehead skin of certain human volunteers.
F S Fein et al.
Archives of pathology & laboratory medicine, 107(9), 480-483 (1983-09-01)
The pathogenesis of the cardiomyopathy associated with diabetes mellitus is unknown. Among several suggested mechanisms, myocardial necrosis induced by endogenous catecholamines may play a role. Therefore, the sensitivity of the heart to the effect of varying doses of isoproterenol hydrochloride
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I2760-100MG | 04061833848616 |
| I2760-1G | 04061833848623 |
| I2760-500MG | 04061833848630 |