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M5655

噻唑蓝

Name: 噻唑蓝
Brand: SIGMA

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)

别名:

3-(4,5-二甲基-2-噻唑)-2,5-二苯基溴化四氮唑噻唑蓝, 噻唑四唑蓝溴化盐, 噻唑蓝四唑蓝

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关于此项目

经验公式（希尔记法）:

C₁₈H₁₆BrN₅S

化学文摘社编号:

298-93-1

分子量:

414.32

UNSPSC Code:

12352207

NACRES:

NA.75

PubChem Substance ID:

24897030

EC Number:

206-069-5

Beilstein/REAXYS Number:

4081397

MDL number:

MFCD00011964

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属性

product line

BioReagent

Quality Level

200

assay

≥97.5% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

mp

195 °C (dec.) (lit.)

solubility

H₂O: 5 mg/mL

storage temp.

2-8°C

SMILES string

[Br-].Cc1nc(sc1C)-[n+]2nc(nn2-c3ccccc3)-c4ccccc4

InChI

1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

InChI key

AZKSAVLVSZKNRD-UHFFFAOYSA-M

说明

Application

噻唑蓝溴化四唑已在细胞活力测定（MTT测定）中被用作比色代谢活性指示剂。它还被用于测定细胞增殖。

噻唑蓝四唑蓝(MTT)可用于细胞增殖的检测。 MTT产生一种淡黄色的溶液，通过活细胞的线粒体脱氢酶将其转化为深蓝色、不溶于水的MTT福尔马赞。该蓝色晶体可溶于酸化异丙醇，可采用比色法测定其570 nm处的强度。

噻唑蓝四唑蓝(MTT)可用于细胞增殖的检测。 MTT产生一种淡黄色的溶液，通过活细胞的线粒体脱氢酶将其转化为深蓝色、不溶于水的MTT福尔马赞。该蓝色晶体可溶于酸化异丙醇，可采用比色法测定其570 nm处的强度。MTT已被用作组织化学/细胞化学试剂以及用于检测NAD。由于所使用的氰化物陷阱可与阳离子结合，组织中的ADP-连接酶系统无法采用MTT检测。 MTT迅速还原为福尔马赞，福尔马赞与镍、铜和钴螯合;钴螯合物已可用于氧化体系。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H315,H319,H335,H341

pcodes

P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

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全球贸易项目编号

货号	GTIN
M5655-500MG	04061835568895
M5655-100MG	04061835568871
M5655-5X1G	04061835568901
M5655-1G	04061835568888
M5655-15MG	04061833697962