M9808
抗 毒蕈碱乙酰胆碱受体 (M 1 ) 兔抗
affinity isolated antibody, lyophilized powder
别名:
乙酰胆碱受体抗体
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse, rat
technique(s)
immunoblotting: 1:200 using rat brain membranes, immunohistochemistry: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CHRM1(1128)
rat ... Chrm1(25229)
General description
毒蕈碱乙酰胆碱受体1（M1）属于A类G蛋白偶联受体（GPCR）家族的一员，由CHRM1基因所编码。毒蕈碱受体具有位于副交感神经突触下膜上的七个跨膜结构域。CHRM1基因位于人染色体11q12.3上。
毒蕈碱胆碱能受体1（M1）在大鼠的前脑中可见。
Immunogen
人 M 1 毒蕈碱乙酰胆碱受体 (mAChR) 的 i3 胞内环的一部分的 GST 融合蛋白，对应于 227-353 氨基酸残基。1、 2
Biochem/physiol Actions
毒蕈碱乙酰胆碱受体1（M1）可调节正常的前列腺生长和降低水平的腺体分泌。毒蕈碱受体可在肿瘤进展中起主要作用。毒蕈碱乙酰胆碱受体（mAChR）可调节腺苷酸环化酶和钾通道活性。它还可刺激各种丝裂原活化蛋白激酶。M1可能有助于发现阿尔茨海默′病的治疗方法。
研究表明，大鼠中毒蕈碱胆碱能受体1（M1）的激活会导致肝脏内毒素耐受性出现变化。
Physical form
从含有1%牛血清白蛋白和0.05%叠氮化钠的磷酸盐缓冲盐水（pH 7.4）中冻干。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
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