P6126
(R)-(−)-去氧肾上腺素 盐酸盐
≥99% (titration), powder, α₁-adrenoceptor agonist
别名:
(R)-(−)-1-(3-羟基苯基)-2-甲氨基乙醇 盐酸盐, (R)-(−)-3-羟基-α-(甲氨基乙基)苄醇 盐酸盐
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关于此项目
线性分子式:
HOC6H4CH(CH2NHCH3)OH·HCl
化学文摘社编号:
分子量:
203.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-517-3
MDL number:
Beilstein/REAXYS Number:
4158948
Form:
powder
Quality level:
产品名称
(R)-(−)-去氧肾上腺素 盐酸盐, powder
form
powder
Quality Level
mp
143-145 °C (lit.)
originator
Johnson & Johnson
SMILES string
OC1=CC([C@H](CNC)O)=CC=C1.Cl
InChI
1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key
OCYSGIYOVXAGKQ-FVGYRXGTSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
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General description
(R)-(-)-去氧肾上腺素盐酸盐是一种肾上腺素能药，其作为 β-受体拟交感神经药。
Application
(R)-(-)-去氧肾上腺素盐酸盐已用于：
- 心肌细胞和成纤维细胞的制备和培养
- 刺激心肌条以测量 slice 收缩
- 在原代心肌细胞培养中研究 Kruppel 样因子（KLF）对体内心肌肥大的影响
- 评估胚胎干细胞（ESC）衍生的心肌细胞的药理反应
- 从药理学上挽救早期胚胎致死性的 GATA（类胡萝卜素转录因子）结合蛋白 3（GATA3）空胚
Biochem/physiol Actions
α1-肾上腺素受体激动剂。
Features and Benefits
该化合物由 Johnson & Johnson 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单， 请单击此处。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1B
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
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Effect of basic fibroblast growth factor on cardiomyocyte differentiation from mouse embryonic stem cells.
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Bhavsar PK, et al.
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商品
Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P6126-25G | 04061834392958 |
| P6126-50G | 04061832092768 |
| P6126-5G | 04061835253418 |
| P6126-10G | 04061834392941 |
| P6126-100G | 04061835253401 |
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