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Merck
CN

AV32301

Anti-THRAP5 antibody produced in rabbit

IgG fraction of antiserum

别名:

Anti-Thyroid hormone receptor associated protein 5

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1
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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

97 kDa

species reactivity

pig, human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... THRAP5(10025)

General description

THRAP5 (MED16) is a component of the Mediator complex required for facilitating the functions of transcriptional activators. This component is known to function as a coactivator for heat-shock-induced and lipopolysaccharide transcriptional stimulators.
Rabbit Anti-MED16 antibody recognizes human, mouse, rat, and canine MED16.

Immunogen

Synthetic peptide directed towards the C terminal region of human THRAP5

Application

Rabbit Anti-THRAP5 antibody can be used for western blot (0.12μg/ml) and IHC (4-8μg/ml) assays.

Biochem/physiol Actions

THRAP5 is part of the human thyroid hormone receptor-associated protein (TRAP)-Mediator family which acts as a coactivator for a broad range of nuclear hormone receptors as well as other classes of transcriptional activators.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: RLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLGACPTEECKAC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tae Whan Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(33), 12153-12158 (2004-08-07)
Transcriptional activators interact with diverse proteins and recruit transcriptional machinery to the activated promoter. Recruitment of the Mediator complex by transcriptional activators is usually the key step in transcriptional activation. However, it is unclear how Mediator recognizes different types of

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