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Merck
CN

C7911

伴刀豆球蛋白A 来源于洋刀豆 (刀豆)

agarose conjugate, Type III-ASCL, saline suspension

别名:

刀豆素 A

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化学文摘社编号:
UNSPSC Code:
12161501
EC Number:
234-258-2
MDL number:
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conjugate

agarose conjugate

type

Type III-ASCL

form

saline suspension

extent of labeling

~10 mg per mL

matrix

4% cross-linked beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

~10 mg/mL binding capacity (peroxidase (P 8375))(pH 6.0), ~6 mg/mL binding capacity (yeast mannan)(pH 7.2)

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

刀豆素 A 无血型特异性,但对末端 α-D-甘露糖基和 α-D-葡糖基残基具有亲和力。需要 Ca2+ 和 Mn2+ 离子存在才能显示活性。刀豆素 A 在 pH 6.5 或更低的条件下解离为二聚体。pH 在 5.8 至 7.0 之间时,刀豆素 A 以四聚体形式存在;pH 高于 7.0 时,形成更高的聚合体。根据聚合程度不同,刀豆素 A 可能显示出具有促有丝分裂的活性。琥珀酰化可以生成一种能够在 pH 高于 5.6 时仍保持二聚体形式的活性二聚体。

Physical form

Suspension in 1.0 M NaCl containing 1 mM CaCl2, 1 mM MgCl2, 1 mM MnCl2 and 0.02% thimerosal

Preparation Note

One mL suspension yields approx. 0.5 ml gel.

Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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