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F1678

R-(−)-Fluoxetine hydrochloride

Name: R-(−)-Fluoxetine hydrochloride
Brand: SIGMA

>98% (HPLC), solid

别名:

(R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride

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关于此项目

经验公式（希尔记法）:

C₁₇H₁₈NOF₃ · HCl

化学文摘社编号:

114247-09-5

分子量:

345.79

NACRES:

NA.77

PubChem Substance ID:

24278433

UNSPSC Code:

12352200

MDL number:

MFCD04040065

Assay:

>98% (HPLC)

Form:

solid

Storage condition:

desiccated

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属性

Quality Segment

100

assay

>98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H₂O: soluble >10 mg/mL

originator

Eli Lilly

SMILES string

Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1

InChI key

GIYXAJPCNFJEHY-PKLMIRHRSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

说明

Application

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

to study its effects on the embryoid body (EB) morphogenesis
in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
to study its effects as an endocrine disruption inducer in Pimephales promelas

Biochem/physiol Actions

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H315,H318

pcodes

P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号	GTIN
F1678-5MG	04061832090825
F1678-25MG	04061832090818