H1775
Monoclonal Anti-Heat Shock Protein 90 antibody produced in mouse
clone AC-16, ascites fluid
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
AC-16, monoclonal
Application:
microarray
western blot
western blot
Species reactivity:
wheat germ, chicken, Sf9 cell line, rabbit, rat, human, mouse, Achlya
Citations:
29
Technique(s):
microarray: suitable
western blot: 1:1,000 using cultured human foreskin fibroblasts
western blot: 1:1,000 using cultured human foreskin fibroblasts
Uniprot accession no.:
产品名称
Monoclonal Anti-Heat Shock Protein 90 antibody produced in mouse, clone AC-16, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
AC-16, monoclonal
mol wt
antigen 88 kDa
contains
15 mM sodium azide
species reactivity
wheat germ, chicken, Sf9 cell line, rabbit, rat, human, mouse, Achlya
packaging
antibody small pack of 25 μL
technique(s)
microarray: suitable
western blot: 1:1,000 using cultured human foreskin fibroblasts
isotype
IgG2b
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HSP90AA1(3320), HSP90AB1(3326)
mouse ... Hsp90aa1(15519), Hsp90ab1(15516)
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
Monoclonal Anti-Heat Shock Protein 90 antibody has been used in ovarian histomorphology, immunohistochemistry and western blotting.
Biochem/physiol Actions
HSP90AB1 (heat shock protein 90α family class B member 1) participates in signal transduction, protein folding and degradation, and morphological evolution. It is required for the transport of client proteins between the cytoplasm and nucleus. In lung adenocarcinoma patients, overexpression of HSP90AB1 in non-small cell lung cancer tissues results in imperfect clinical predictions. Suppression of this gene reduces the potential of endothelial cells to form tube structures.
The antibody is reactive with both the constitutive and the inducible forms of HSP90. However, it does not bind to the native form of HSP90. It does not recognize HSP90 from E. coli and yeast.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
HSP90AB1 (heat shock protein 90α family class B member 1) belongs to the Hsp90 family. It consists of major members-Hsp90α, Hsp90β, GRP94 (glucose-regulated protein 94) and Hsp75. It is located on chromosome 6p21. HSP90AB1is an ATP-dependent molecular chaperone, having a molecular weight of 90kDa. HSP90AA1 is located on human chromosome 14q32.31.
Immunogen
heat shock protein 90 (HSP90) from the water mold Achlya ambisexualis
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Exposure to chemical cocktails before or after conception-the effect of timing on ovarian development
Bellingham M, et al.
Molecular and Cellular Endocrinology, 376(1-2), 156-172 (2013)
X-S Liu et al.
Oncogene, 35(23), 3071-3078 (2015-10-13)
We recently reported that ZBTB7A is a bona fide transcription repressor of key glycolytic genes and its downregulation in human cancer contributes to tumor metabolism. As reduced expression of ZBTB7A is found only in a subset of human cancers, we
t (3; 14)(q27; q32) HSP90AA1/BCL6
Huret J L.
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2013)
Antioxidant and molecular chaperone defences during estivation and arousal in the South American apple snail Pomacea canaliculata
Giraud B M, et al.
The Journal of Experimental Biology, 216(4), 614-622 (2013)
Hsp90AB1 Protein is Overexpressed in Non-small Cell Lung Cancer Tissues and Associated with Poor Prognosis in Lung Adenocarcinoma Patients
Wang M, et al.
Chinese Journal of Analytical Chemistry, 19(2), 64-69 (2016)
商品
Quantitative and qualitative western blotting to validate knockdown by esiRNA.
相关内容
Instructions
Datasheet
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持