P1985
Platelet-Derived Growth Factor Soluble Receptor α human
>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
别名:
PDGF sRα
生物来源
human
重组
expressed in NSO cells
方案
>97% (SDS-PAGE)
表单
lyophilized powder
效能
5-10 μg/mL ED50
分子量
predicted mol wt ~56 kDa
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... PDGFRA(5156)
生化/生理作用
Member of the class III subfamily of receptor tyrosine kinases; binds all three PDGF isoforms with high affinity and induces receptor homo-and heterodimerization and signal transduction.
Recombinant human platelet-derived growth factor soluble receptor α, a member of the class III subfamily of receptor tyrosine kinases, binds all three PDGF isoforms with high affinity and induces receptor homo-and heterodimerization and signal transduction.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin
分析说明
The bioactivity is measured by its ability to inhibit human PDGF-AB or recombinant human PDGF-AA in quiescent NR6R-3T3 fibroblasts.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
L Claesson-Welsh et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(13), 4917-4921 (1989-07-01)
The primary structure of the human A-type receptor for platelet-derived growth factor (PDGF) has been determined. A 6.5-kilobase (kb) transcript was identified through low-stringency hybridization with a probe derived from the B-type PDGF receptor cDNA. The sequence of a cDNA
Heldin, C.H., et al. et al.
Guidebook to Cytokines and Their Receptors, 202-202 (1994)
Purification of human platelet-derived growth factor.
E W Raines et al.
Methods in enzymology, 109, 749-773 (1985-01-01)
相关内容
Datasheet
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