生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen ~120 kDa
种属反应性
human
浓度
~1.0 mg/mL
技术
immunoprecipitation (IP): 5.0-10 μg
indirect immunofluorescence: 1.25-2.5 μg/mL using fixed HEK-293T cells
western blot: 1-2 μg/mL using HeLa cell lysates
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... IPO9(55705)
mouse ... Ipo9(226432)
rat ... Ipo9(304817)
一般描述
Importin 9 (IPO9) is encoded by the gene mapped to human chromosome 1q32.1. The encoded protein is a molecular transporter and chaperone and is a member of karyopherins super-family. IPO9 has a molecular weight of ~110kDa.
特异性
Anti-Importin 9 (N-terminal) recognizes human Importin 9.
免疫原
synthetic peptide corresponding to amino acids 90-105 of human Importin 9 conjugated to KLH. The corresponding sequence is identical in mouse and rat.
应用
Anti-Importin 9 (N-terminal) antibody produced in rabbit may be used in:
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化/生理作用
Importin 9 (IPO9) promotes transcriptional activity by actively regulating nuclear actin levels. The encoded protein facilitates transport of ribosomal proteins and core histones into the nucleus. Additionally, it acts as an import receptor for c-Jun. Elevated expression of Ipo9 decreased and knockdown of Ipo9 increased basal type I interferon (IFN)-ε expression.
Importin 9 is an import factor for many proteins, including the hepatocellular carcinoma associated protein, core histone H2B and the heat shock protein, HSP27.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
储存及稳定性
For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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