SAB4200394
抗-巢蛋白（C端） 兔抗
~1.5 mg/mL, affinity isolated antibody
别名:
抗NES
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
11
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~300 kDa
species reactivity
mouse, rat
packaging
antibody small pack of 25 μL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
~1.5 mg/mL
technique(s)
indirect immunofluorescence: 1-2 μg/mL using mouse P19 cells, western blot: 2-4 μg/mL using lysates of HEK293T cells over-expressing rat nestin.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Nes(18008)
rat ... Nes(25491)
General description
巢蛋白/NES属于中间丝（IF）蛋白家族的成员。在未成熟的神经上皮和祖细胞类型中发现其表达。这个240 kDa的蛋白质包含最短的头部结构域（N末端）和一个长的尾部结构域（C末端）。巢蛋白位于人染色体1q23.1。
Immunogen
该合成肽与KLH偶联，其对应于小鼠巢蛋白的C端序列。该序列在大鼠巢蛋白中是相同的。
Application
抗-巢蛋白（C端）抗体可用于免疫染色分析。
Biochem/physiol Actions
巢蛋白/NES在调节中间丝的组装和拆卸中起主要作用，进而帮助细胞与其他结构蛋白一起重塑。
Physical form
0.01M磷酸盐缓冲盐水溶液，pH 7.4，含有15 mM叠氮化钠。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Nestin structure and predicted function in cellular cytoskeletal organisation.
Michalczyk K and Ziman M
Histology and Histopathology, 20(2), 665-671 (2005)
YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation.
Huang Z, et al.
Development, 143(13), 2398-2409 (2016)
The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons.
Zhu B, et al.
Biochemical and Biophysical Research Communications, 500(3), 645-649 (2018)
Intermediate filaments in peripheral nervous system: Their expression, dysfunction and diseases
Parlakian A, et al.
Revista de Neurologia, 172(10), 607-613 (2016)
Stephen E McGowan et al.
American journal of physiology. Lung cellular and molecular physiology, 315(1), L102-L115 (2018-03-16)
Generation of secondary alveolar septa occurs primarily after birth in humans and is complete in mice postnatally, when mechanical stresses vary as air space pressure oscillates. Alveolar mesenchymal cells deposit elastic fibers, which limit cell strain; although when the elastic
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