SAB4300170
Anti-phospho-TH (pSer40) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-TYH antibody produced in rabbit, Anti-tyrosine hydroxylase antibody produced in rabbit
产品名称
Anti-phospho-TH (pSer40) antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
55-60 kDa
species reactivity
mouse, rat, human
concentration
1 mg/mL
technique(s)
indirect immunofluorescence: 1:100-1:200
isotype
IgG
immunogen sequence
(R-Q-SP-L-I)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer40)
Quality Level
Gene Information
human ... TH(7054)
Features and Benefits
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General description
The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen
Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I), according to the protein TH.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Kyoung In Kim et al.
Experimental neurobiology, 28(2), 289-299 (2019-05-30)
Transient receptor potential vanilloid subtype 1 (TRPV1) on astrocytes prevents ongoing degeneration of nigrostriatal dopamine (DA) neurons in MPP+-lesioned rats via ciliary neurotrophic factor (CNTF). The present study determined whether such a beneficial effect of astrocytic TRPV1 could be achieved
Bárbara Rangel da Silva et al.
Cellular and molecular neurobiology, 39(1), 99-109 (2018-11-16)
Neurospheres prepared from multipotent progenitors in the retina obtained from postnatal mice differentiate into neurons and Müller glia (De Melo Reis et al., in Cell Mol Neurobiol 31:835-846, 2011). Here, we investigated whether neurospheres prepared from adult chickens (ciliary marginal
Rosilane Taveira-da-Silva et al.
Kidney & blood pressure research, 44(1), 1-11 (2019-02-28)
Dopamine (DA) is a natriuretic hormone that inhibits renal sodium reabsorption, being Angiotensin II (Ang II) its powerful counterpart. These two systems work together to maintain sodium homeostasis and consequently, the blood pressure (BP) within normal limits. We hypothesized that
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