SAB4501285
Anti-TRIM59 antibody produced in rabbit
affinity isolated antibody
别名:
RING finger protein 104, Tumor suppressor TSBF-1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 47 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TRIM59(286827)
General description
Anti-TRIM59 Antibody detects endogenous levels of total TRIM59 protein.
TRIM59 (tripartite-59) belongs to the tripartite motif (TRIM) family of proteins. It has a RING domain, one or two B-box motifs and a coiled-coil region. It is located on human chromosome 3q25.
Immunogen
The antiserum was produced against synthesized peptide derived from human TRIM59.
Immunogen Range: 191-240
Immunogen Range: 191-240
Biochem/physiol Actions
Suppression of tripartite-59 (TRIM59) blocks the multiplication and migration of cervical cancer cells. In prostate cancer models, TRIM59 serves as a proto-oncogene that affects Ras and RB signal pathways. It also induces the multiplication and migration of non-small cell lung cancer cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation
Spolnicka M, et al.
Clinical epigenetics (2016)
Knockdown of Tripartite-59 (TRIM59) Inhibits Cellular Proliferation and Migration in Human Cervical Cancer Cells
Aierken G, et al.
Oncology Research, 25, 381-388 (2017)
TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins
Zhan W, et al.
PLoS ONE, 10 (2015)
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