SAB4502044
Anti-ZNF295 antibody produced in rabbit
affinity isolated antibody
别名:
KIAA1227, ZBTB21, ZNF295, Zinc finger and BTB domain-containing protein 21, Zinc finger protein 295
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 118 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, immunohistochemistry: 1:50-1:100
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ZNF295(49854)
General description
Anti-ZNF295 Antibody detects endogenous levels of total ZNF295 protein.
The gene ZBTB21 (zinc finger and BTB domain containing 21) is mapped to human chromosome 21q22.3. The protein contains a BTB (broad-complex, tramtrack and bric a brac)/POZ (poxvirus and zinc finger) domain and multiple kruppel (C2H2) type zinc finger domains. ZBTB21 is part of the POK (POZ and krüppel) transcription factor family of proteins. It is widely expressed in human tissues.
The gene ZBTB21 (zinc finger and BTB domain containing 21) is mapped to human chromosome 21q22.3. The protein contains a BTB (broad-complex, tramtrack and bric a brac)/POZ (poxvirus and zinc finger) domain and multiple kruppel (C2H2) type zinc finger domains. ZBTB21 is part of the POK (POZ and krüppel) transcription factor family of proteins. It is widely expressed in human tissues.
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF295.
Immunogen Range: 731-780
Immunogen Range: 731-780
Biochem/physiol Actions
ZBTB21 (zinc finger and BTB domain containing 21) is a transcription repressor. It interacts with ZFP161 (zinc finger protein 161) and might be associated with the bi-directional control of gene expression.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
M Reza Sailani et al.
Genome research, 23(9), 1410-1421 (2013-06-21)
Congenital heart defect (CHD) occurs in 40% of Down syndrome (DS) cases. While carrying three copies of chromosome 21 increases the risk for CHD, trisomy 21 itself is not sufficient to cause CHD. Thus, additional genetic variation and/or environmental factors
Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.
Jun Wang et al.
Biochemical and biophysical research communications, 327(2), 615-627 (2005-01-05)
Human ZNF295 protein harbors a BTB/POZ domain and multiple krüppel (C(2)H(2)) type zinc finger domains, and thus belongs to a family of POK (POZ and krüppel) transcription factor. We have identified many transcript variants generated by the alternative splicing in
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