SAB4502044
Anti-ZNF295 antibody produced in rabbit
affinity isolated antibody
别名:
KIAA1227, ZBTB21, ZNF295, Zinc finger and BTB domain-containing protein 21, Zinc finger protein 295
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 118 kDa
种属反应性
mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
NCBI登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ZNF295(49854)
一般描述
Anti-ZNF295 Antibody detects endogenous levels of total ZNF295 protein.
The gene ZBTB21 (zinc finger and BTB domain containing 21) is mapped to human chromosome 21q22.3. The protein contains a BTB (broad-complex, tramtrack and bric a brac)/POZ (poxvirus and zinc finger) domain and multiple kruppel (C2H2) type zinc finger domains. ZBTB21 is part of the POK (POZ and krüppel) transcription factor family of proteins. It is widely expressed in human tissues.
The gene ZBTB21 (zinc finger and BTB domain containing 21) is mapped to human chromosome 21q22.3. The protein contains a BTB (broad-complex, tramtrack and bric a brac)/POZ (poxvirus and zinc finger) domain and multiple kruppel (C2H2) type zinc finger domains. ZBTB21 is part of the POK (POZ and krüppel) transcription factor family of proteins. It is widely expressed in human tissues.
免疫原
The antiserum was produced against synthesized peptide derived from human ZNF295.
Immunogen Range: 731-780
Immunogen Range: 731-780
生化/生理作用
ZBTB21 (zinc finger and BTB domain containing 21) is a transcription repressor. It interacts with ZFP161 (zinc finger protein 161) and might be associated with the bi-directional control of gene expression.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
M Reza Sailani et al.
Genome research, 23(9), 1410-1421 (2013-06-21)
Congenital heart defect (CHD) occurs in 40% of Down syndrome (DS) cases. While carrying three copies of chromosome 21 increases the risk for CHD, trisomy 21 itself is not sufficient to cause CHD. Thus, additional genetic variation and/or environmental factors
Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.
Jun Wang et al.
Biochemical and biophysical research communications, 327(2), 615-627 (2005-01-05)
Human ZNF295 protein harbors a BTB/POZ domain and multiple krüppel (C(2)H(2)) type zinc finger domains, and thus belongs to a family of POK (POZ and krüppel) transcription factor. We have identified many transcript variants generated by the alternative splicing in
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