产品名称
Anti-TP53INP2 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 23 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TP53INP2(58476)
mouse ... T53I2(68728)
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Biochem/physiol Actions
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) acts as a promoter of autophagy and is involved in cell catabolism. It is essential for rDNA transcription. TP53INP2 is required for protein synthesis and cell proliferation. It also acts as a coactivator of the thyroid hormone receptor and regulates the activities of thyroid hormone.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-TP53INP2 Antibody detects endogenous levels of total TP53INP2 protein.
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) is located in the nucleolus. It is ubiquitously present in the tissues, with a high metabolism level. TP53INP2 is located on human chromosome 20q11.22.
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) is located in the nucleolus. It is ubiquitously present in the tissues, with a high metabolism level. TP53INP2 is located on human chromosome 20q11.22.
Immunogen
The antiserum was produced against synthesized peptide derived from human TP53INP2.
Immunogen Range: 1-50
Immunogen Range: 1-50
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters.
Xu Y, et al.
Autophagy, 12(7), 1118-1128 (2016)
Takaya Ishihara et al.
Cancer science, 99(10), 1940-1949 (2008-11-20)
Anaplastic thyroid carcinoma (ATC) is one of the most virulent of all human malignancies, with a mean survival time among patients of less than 1 year after diagnosis. To date, however, cytogenetic information on this disease has been very limited.
Hamish Crerar et al.
Neuron, 102(3), 553-563 (2019-03-12)
Neurons are extraordinarily large and highly polarized cells that require rapid and efficient communication between cell bodies and axons over long distances. In peripheral neurons, transcripts are transported along axons to growth cones, where they are rapidly translated in response
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