产品名称
抗体-N6-甲基腺苷(m6A)抗体,兔单克隆, recombinant, expressed in HEK 293 cells, clone RM362, purified immunoglobulin
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM362, monoclonal
recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
vertebrates, human
technique(s)
ELISA: 0.1-3 μg/mL
dot blot: 0.5-2 μg/mL
immunocytochemistry: 0.1— 3 μg/mL
immunoprecipitation (IP): .2-5 μg/mL (Methylated RNA)
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... METTL3(56339)
Biochem/physiol Actions
该抗体对RNA和DNA中的N6-甲基腺苷(m6A)均有反应。与非甲基化的腺苷无交叉反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
Immunogen
BSA偶联的N6-甲基腺苷
Physical form
溶于含有50%甘油/PBS、1%BSA和0.09%叠氮化钠的磷酸盐缓冲液中。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
此项目有
Shuai Ren et al.
Annals of translational medicine, 11(1), 15-15 (2023-02-11)
Keloid is a dermal fibrotic disease characterized by excessive proliferation of dermal fibroblasts and deposition of excessive collagen. N6-methyladenosine (m6A) plays a significant role in numerous physiological and pathological regulatory processes in the human body. Fat mass and obesity-associated protein
Fang Wang et al.
Chinese medicine, 18(1), 122-122 (2023-09-22)
Curdione is a sesquiterpene isolated from Curcumae Rhizoma that possesses high biological activity and extensive pharmacological effects. As a traditional Chinese medicine, Curcumae Rhizoma can inhibit the development of many types of cancer, especially colorectal cancer. However, the anti-colorectal mechanism
Yufan Ying et al.
Molecular cancer, 23(1), 79-79 (2024-04-25)
R-loops are prevalent three-stranded nucleic acid structures, comprising a DNA-RNA hybrid and a displaced single-stranded DNA, that frequently form during transcription and may be attributed to genomic stability and gene expression regulation. It was recently discovered that RNA modification contributes
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