重组
expressed in HEK 293 cells
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
RM362, monoclonal
recombinant monoclonal
表单
buffered aqueous glycerol solution
种属反应性
vertebrates, human
技术
ELISA: 0.1-3 μg/mL
dot blot: 0.5-2 μg/mL
immunocytochemistry: 0.1— 3 μg/mL
immunoprecipitation (IP): .2-5 μg/mL (Methylated RNA)
同位素/亚型
IgG
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... METTL3(56339)
免疫原
BSA偶联的N6-甲基腺苷
生化/生理作用
该抗体对RNA和DNA中的N6-甲基腺苷(m6A)均有反应。与非甲基化的腺苷无交叉反应。
外形
溶于含有50％甘油/PBS、1％BSA和0.09％叠氮化钠的磷酸盐缓冲液中。
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
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Annals of translational medicine, 11(1), 15-15 (2023-02-11)
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Molecular cancer, 23(1), 79-79 (2024-04-25)
R-loops are prevalent three-stranded nucleic acid structures, comprising a DNA-RNA hybrid and a displaced single-stranded DNA, that frequently form during transcription and may be attributed to genomic stability and gene expression regulation. It was recently discovered that RNA modification contributes
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