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Merck
CN

1601827

USP

三氯乙烯 溶液

United States Pharmacopeia (USP) Reference Standard

别名:

三氯代乙烯

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化学文摘社编号:
MDL number:
UNSPSC Code:
41116107
EC Number:
201-167-4
NACRES:
NA.24
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产品名称

三氯乙烯 溶液, United States Pharmacopeia (USP) Reference Standard

SMILES string

ClC(=CCl)Cl

InChI key

XSTXAVWGXDQKEL-UHFFFAOYSA-N

InChI

1S/C2HCl3/c3-1-2(4)5/h1H

grade

pharmaceutical primary standard

form

solution

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

single component solution

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Residual Solvent Class 2 - Trichloroethylene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

closed cup - does not flash

flash_point_c

closed cup - does not flash

法规信息

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分析证书(COA)

Lot/Batch Number

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Fariha Zaheer et al.
Neurologic clinics, 29(3), 657-665 (2011-08-02)
Multiple genetic and environmental etiologies have been implicated in the pathogenesis of idiopathic Parkinson disease. Recent observations have suggested an association between chronic exposure to trichloroethylene (TCE) and development of clinical parkinsonism. Animal models of TCE exposure have shown nigrostriatal
Prabhakar Pant et al.
Journal of environmental sciences (China), 22(1), 116-126 (2010-04-20)
Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen
Hang Zhang et al.
Biochemical and biophysical research communications, 446(2), 590-595 (2014-03-19)
Trichloroethylene (TCE), a major occupational and environmental pollutant, has been recently associated with aberrant epigenetic changes in experimental animals and cultured cells. TCE is known to cause severe hepatotoxicity; however, the association between epigenetic alterations and TCE-induced hepatotoxicity are not
Shams Tabrez et al.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 27(3), 178-196 (2009-08-07)
Trichloroethylene (TCE) is a prevalent occupational and environmental contaminant that has been reported to cause a variety of toxic effects. This article reviews toxicity, mutagenicity, and carcinogenicity caused by the exposure of TCE and its metabolites in the living system
Michihiro Kamijima et al.
International archives of occupational and environmental health, 80(5), 357-370 (2006-11-16)
Workers exposed to trichloroethylene (TCE) rarely show severe generalized skin disorders and accompanying hepatitis which resemble drug hypersensitivities. The disorders are completely different from solvent-induced irritating contact dermatitis, and their serious consequences have become one of the critical occupational health

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