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Veli C Ozalp et al.
Analytica chimica acta, 853, 533-540 (2014-12-04)
A quartz crystal microbalance sensor (QCM) was developed for sensitive and specific detection of Salmonella enterica serovar typhimurium cells in food samples by integrating a magnetic bead purification system. Although many sensor formats based on bioaffinity agents have been developed
Jocie F Cherry et al.
Acta biomaterialia, 10(10), 4113-4126 (2014-06-11)
We investigated the design of neurotrophic biomaterial constructs for human neural stem cells, guided by neural developmental cues of N-cadherin and L1 adhesion molecules. Polymer substrates fabricated either as two-dimensional (2-D) films or three-dimensional (3-D) microfibrous scaffolds were functionalized with
Hisako Hikiji et al.
Journal of materials science. Materials in medicine, 25(6), 1531-1538 (2014-02-28)
Rapid and efficient animal models are needed for evaluating the effectiveness of many new candidate bone regenerative materials. We developed an in vivo model screening for calvarial bone regeneration in lipopolysaccharide (LPS)-treated mice, in which materials were overlaid on the
Aline Debrassi et al.
Langmuir : the ACS journal of surfaces and colloids, 31(20), 5633-5644 (2015-04-29)
Porous aluminum oxide (PAO) is a nanoporous material used for various (bio)technological applications, and tailoring its surface properties via covalent modification is a way to expand and refine its application. Specific and complex chemical modification of the PAO surface requires
Mi Hee Lee et al.
Biomedical materials (Bristol, England), 10(5), 055010-055010 (2015-09-24)
Intimal hyperplasia is an excessive ingrowth of tissue resulting in chronic structural lesions commonly found at sites of atherosclerotic lesions, arterial angioplasty, vascular graft anastomoses, and other vascular abnormalities. Epigallocatechin-3-O-gallate (EGCG) was shown to elicit antioxidant, anti-proliferative, and anti-thrombogenic effects.
Haitao Huang et al.
Colloids and surfaces. B, Biointerfaces, 133, 362-369 (2015-07-06)
In this study, a novel micellar drug carrier was fabricated from an amphiphilic diblock copolymer containing poly (ethylene glycol) monomethyl ether (mPEG) and stearic moiety (C18) with a linkage of valine-citrulline (VC), which can be cleaved by cathepsin B (CB)
B M Sadler et al.
Journal of clinical pharmacology, 41(4), 386-396 (2001-04-18)
The objective of this study was to determine the metabolic profile, routes of elimination, and total recovery of amprenavir and its metabolites after a single oral dose of [14C]-amprenavir. Six healthy male subjects each received a single oral 630 mg
Eduardo Ruvolo Junior et al.
Photodermatology, photoimmunology & photomedicine, 30(4), 202-211 (2014-01-15)
In the past 56 years, many different in vitro methodologies have been developed and published to assess the sun protection factor (SPF) of products, but there is no method that has 1:1 correlation with in vivo measurements. Spectroscopic techniques have
Ali Akbar Asgharinezhad et al.
Analytica chimica acta, 844, 80-89 (2014-08-31)
In this study, diverse types of Fe3O4 nanocomposites modified by polyaniline, polypyrrole, and aniline-pyrrole copolymer were synthesized through chemical oxidative polymerization process for dispersive-μ-solid phase extraction (D-μ-SPE) in the presence of various dopants. The results showed that the nanocomposite modified
Navjot Kaur et al.
Neuron, 107(6), 1197-1211 (2020-07-25)
Neural stem cells directly or indirectly generate all neurons and macroglial cells and guide migrating neurons by using a palisade-like scaffold made of their radial fibers. Here, we describe an unexpected role for the radial fiber scaffold in directing corticospinal
Piotr Luliński et al.
Journal of chromatography. A, 1420, 16-25 (2015-10-16)
In this paper, the optimized synthesis and detailed characterization of novel imprinted material for selective extraction of 2-aminothiazoline-4-carboxylic acid (ATCA) were described. The prepolymeric system contained 1-allyl-2-thiourea and ethylene glycol dimethacrylate in methanol, tetrahydrofuran and dimethyl sulfoxide porogenic mixture and
Krista L Niece et al.
Antimicrobial agents and chemotherapy, 59(9), 5542-5547 (2015-07-01)
Colistin use has increased in response to the advent of infections caused by multidrug-resistant organisms. It is administered parenterally as an inactive prodrug, colistin methanesulfonate (CMS). Various formulations of CMS and labeling conventions can lead to confusion about colistin dosing
S Bag et al.
Organic & biomolecular chemistry, 13(6), 1763-1767 (2014-12-17)
Spectroscopic and in cellulo studies are here reported on the very first BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette where the luminol CL agent is covalently linked to the BODIPY energy-transfer acceptor in a molecular dyad. The efficiency of intramolecular CRET
Matthäus Mlynek et al.
Journal of chromatography. A, 1284, 112-117 (2013-03-08)
The behaviour of PMMA standards in mixtures composed of two binary critical eluents was investigated. It was found that combinations of two critical eluents do not result in a molar mass independent elution (critical conditions). When mixing two binary critical
Mengbo Zhou et al.
Biomacromolecules, 16(8), 2308-2315 (2015-07-03)
A new approach toward the fabrication of biocompatible composites suitable for remote melting is presented. It is shown that magnetite nanoparticles (MNP) can be embedded into a matrix of biocompatible thermoplastic dextran esters. For that purpose, fatty acid esters of
Justin A Bogart et al.
Inorganic chemistry, 54(6), 2830-2837 (2015-02-25)
Understanding of the sensitivity of the reduction potential of cerium(IV) cations to ligand field strength has yet to benefit from systematic variation of the ligand environment. Detailed analyses for a series of seven cerium(IV) tetrakis(pyridyl-nitroxide) compounds and their cerium(III) analogues
Amin GhavamiNejad et al.
ACS applied materials & interfaces, 7(22), 12176-12183 (2015-05-20)
Electrospun nanofibers that contain silver nanoparticles (AgNPs) have a strong antibacterial activity that is beneficial to wound healing. However, most of the literature available on the bactericidal effects of this material is based on the use of AgNPs with uncontrolled
M Imbenotte et al.
Forensic science international, 133(1-2), 132-135 (2003-05-14)
In order to analyse a wide range of xenobiotics and their metabolites present in biological fluids, NMR spectroscopy can be used. A large variety of xenobiotics (therapeutic agents, pesticides, solvents, alcohols) can be characterized and quantitated directly, without sample preparation.
Jin Zhang et al.
ChemSusChem, 8(17), 2956-2966 (2015-04-23)
Carbon nanotubes (CNTs) are well known electrocatalyst supports due to their high electrical conductivity, structural stability, and high surface area. Here, we demonstrate that the number of inner tubes or walls of CNTs also have a significant promotion effect on
Biraja C Dash et al.
Biomaterials, 65, 126-139 (2015-07-08)
Critical limb ischemia is a major clinical problem. Despite rigorous treatment regimes, there has been only modest success in reducing the rate of amputations in affected patients. Reduced level of blood flow and enhanced inflammation are the two major pathophysiological
Bibekananda De et al.
Materials science & engineering. C, Materials for biological applications, 56, 74-83 (2015-08-08)
The present work demonstrated a transparent thermosetting nanocomposite with antimicrobial and photoluminescence attributes. The nanocomposites are fabricated by incorporation of different wt.% (1, 2 and 3) of a biocide immobilized OMMT-carbon dot reduced Cu2O nanohybrid (MITH-NH) in the hyperbranched epoxy
M D Smith et al.
Journal of peptide science : an official publication of the European Peptide Society, 5(10), 425-441 (1999-12-02)
The potential of carbohydrate-like tetrahydrofuran frameworks as building blocks with predictable conformational propensities useful in the design and synthesis of novel peptidomimetic materials which adopt well-defined secondary structures is discussed.
Markus Jonek et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15759-15768 (2015-09-24)
4-Phenylsemicarbazide and 1,5-diphenylcarbazide are suitable starting materials for the syntheses of N-heterocyclic carbene (NHC) compounds with new backbone structures. In the first case, cyclisation and subsequent methylation leads to a cationic precursor whose deprotonation affords the triazolon-ylidene 2, which was
Nusheng Chen et al.
Carbohydrate polymers, 128, 122-129 (2015-05-26)
Biocomposites with tunable properties were successfully prepared through ionic assembly between anionic carboxymethyl cellulose (CMC) and cationic copolymers (quaternized poly(l-lactide)-block-poly N,N-dimethylamino-2-ethyl methacrylate) (PLA-b-PDMAEMA). The quaternized PDMAEMA segment not only works as a compatibilizer between hydrophilic CMC and hydrophobic PLA, but
Duo Lu et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(42), 16852-16857 (2012-10-05)
Base excision repair (BER) is a highly conserved DNA repair pathway throughout all kingdoms from bacteria to humans. Whereas several enzymes are required to complete the multistep repair process of damaged bases, apurinic-apyrimidic (AP) endonucleases play an essential role in
Carrie E Brubaker et al.
ACS nano, 9(7), 6872-6881 (2015-07-01)
With proper control over copolymer design and solvation conditions, self-assembled materials display impressive morphological variety that encompasses nanoscale colloids as well as bulk three-dimensional architectures. Here we take advantage of both hydrophobicity and crystallinity to mediate supramolecular self-assembly of spherical
Xiao Liang et al.
Nature communications, 6, 5682-5682 (2015-01-07)
The lithium-sulfur battery is receiving intense interest because its theoretical energy density exceeds that of lithium-ion batteries at much lower cost, but practical applications are still hindered by capacity decay caused by the polysulfide shuttle. Here we report a strategy
Santosh K Misra et al.
PloS one, 10(6), e0125908-e0125908 (2015-06-02)
We present an in-silico-to-in-vitro approach to develop well-defined, self-assembled, rigid-cored polymeric (Polybee) nano-architecture for controlled delivery of a key component of bee venom, melittin. A competitive formulation with lipid-encapsulated (Lipobee) rigid cored micelle is also synthesized. In a series of
Tetrahydrofuran-containing macrolides: a fascinating gift from the deep sea.
Adriana Lorente et al.
Chemical reviews, 113(7), 4567-4610 (2013-03-20)
Michelle A Ouimet et al.
Macromolecular bioscience, 15(3), 342-350 (2014-10-22)
Polymers such as poly(N-vinyl-2-pyrrolidone) (PVP) have been used to prepare hydrogels for wound dressing applications but are not inherently bioactive. For enhanced healing, PVP was blended with salicylic acid-based poly(anhydride-esters) (SAPAE) and shown to exhibit hydrogel properties upon swelling. In
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