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Peptide synthesis
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facet applications:Peptide synthesis
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Base Resins for Peptide Synthesis
Novabiochem® offers polymer supports for solid phase peptide synthesis, suitable for various peptide lengths and sequences.
Biotinylation Reagents
Biotin-labelled peptides find applications in immunology and histochemistry for affinity purification and receptor localization.
Boc Resin Cleavage Protocol
Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.
Chemoselective Purification Tags
Long peptide purification removes impurities effectively, crucial for research and pharmaceutical applications.
Fmoc Resin Cleavage and Deprotection
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
Heterocycle and Cyclic Peptide Formation with N-(isocyamino)triphenylphosphorane (Pinc)
Isocyanides are widely used reagents in organic synthesis, with applications ranging from materials science to drug discovery.
Solving Aspartimide Formation in Fmoc SPPS with Fmoc-Asp(OBno)-OH
Aspartimide formation 1,2 is caused by repeated exposure of aspartic acid-containing sequences to bases like piperidine and can result ultimately in the generation of 9 different by-products.
Peptide Coupling Reagents Guide
Novabiochem® coupling reagents for in situ activation are fast-reacting and compatible with various amino acids.
Peptide Resin Loading Protocols
Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.
Proline Derivatives and Analogs
Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.
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