Protein and nucleic acid interactions

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facet applications:Protein and nucleic acid interactions

facet content type:Technical Article

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Duolink® Proximity Ligation Assay (PLA) Multicolor Kits for Sensitive Multiplex Detection

Duolink® PLA Multicolor technology and the quantification of protein-protein interactions in fixed tissues and cells.

Duolink® PLA Troubleshooting Guide

Support information including tips and tricks, frequently asked questions, and basic troubleshooting.

EGFR-Family Receptor Dimerization Studies

Investigate EGFR and HER2 dimerization in EGFR-family using cell lines and colon tissues as model systems.

FLAG® HA System

The FLAG® HA tandem epitope system consists of small epitopes tags that are not eukaryotic derived. These features minimize interference with protein functions and provide superior specificity.

Fragmentation of chromatin in ChIP

Fragmentation of chromatin in Chromatin Immunoprecipitation (ChIP)

How Proximity Ligation Assays (PLA) Work

Learn how Proximity Ligation Assay technology works and how the protein-protein interaction control kit can confirm in situ detection of EGF-induced EGFR-HER2 dimerization.

Protein-protein Interactions Detection with PLA

Proteins interact with various molecules, including other proteins, to fulfill complex cellular functions within biological systems.

How to Optimize the Duolink® Proximity Ligation Assay

Things to consider for preparation, setup and execution of the Duolink® assay protocol

RNA Immunoprecipitation Chip (RIP) Assay

RNA Immunoprecipitation (RIP) is an essential method for analyzing proteins that interact with and modify the function of mRNAs, small RNAs, viral RNAs, or lncRNAs.

ChIP-X: Cross-linking proteins to DNA and cell lysis

X-ChIP: Cross-linking proteins to DNA and cell lysis

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