- Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).
Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).
Journal of natural products (2008-03-11)
George R Pettit, Fiona Hogan, Jun-Ping Xu, Rui Tan, Toshihiko Nogawa, Zbigniew Cichacz, Robin K Pettit, Jiang Du, Qing-Hua Ye, Gordon M Cragg, Cherry L Herald, Michael S Hoard, Animesh Goswami, Justin Searcy, Larry Tackett, Dennis L Doubek, Lee Williams, John N A Hooper, Jean M Schmidt, Jean-Charles Chapuis, Denise N Tackett, Felicia Craciunescu
PMID18327911
摘要
Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C ( 1), axinastatin 5 ( 5), bengazoles A ( 6), B ( 7), and E ( 8), manzamine A ( 10), jaspamide ( 11), and neoechinulin A ( 19) has been summarized.