[Study on the chemical constituents from fresh roots of Euphorbia fischeriana].

To study the chemical constituents in ethyl acetate fraction from the Euphorbia fischeriana. The compounds were isolated by silica gel column chromatography and HPLC, and their structures were elucidated by means of spectral analyses. Fourteen compounds were identified as 2,4-dihydroxy-6-methoxy-3-methylacetophenone (1), 12-deoxyphorbol-13-hexadecanoate (2), ethylgallate (3), esculetin (4), 2,4-dihydroxy-6-methoxy-acetophenone (5), 12-deoxyphorbol-13-acetate (6), 12-deoxyphorbol-13,20-diacetete (7), jolkinolide B (8), 17-hydroxyjolkinolide B (9), 17-hydroxy-jolkinolide A (10), langduin C (11), 3-methylp-hydroxybenzoic acid (12), methyl gallate (13), 3, 3'-diacetyl-pyridine-4,4'-dimethoxy-2, 2', 6, 6'-tetrahydroxydiphenylmethane (14). Compounds 3, 5, 12, 13 are isolated from this plant for the first time.